Effects of Lycopersicon Esculentum Extract on Hair Growth and Alopecia Prevention

January 2014 in “ PubMed ”

Jae‐Suk Choi, Sung Kyu Jung, Min Hee Jeon, Jin Nam Moon, Wanki Moon, Yi Ji, Inhee Choi, Sang Wook Son

Lycopersicon esculentum extract hair growth alopecia prevention minoxidil vascular endothelial growth factor VEGF keratinocyte growth factor insulin-like growth factor-1 IGF-1 anagen stage hair follicles skin irritation tomato extract Rogaine hair loss prevention growth factors hair growth stage

TLDR Tomato extract can promote hair growth and prevent hair loss without irritating the skin.

A decade ago, a study was conducted to evaluate the potential hair growth-promoting activity of Lycopersicon esculentum extracts. The extracts were applied on the dorsal skin of C57BL/6 mice once a day for 4 weeks. At week 4, the Lycopersicon esculentum extracts showed hair growth-promoting potential similar to that of 3% minoxidil, a common hair growth treatment. The study also found a significant increase in the expression of growth factors such as vascular endothelial growth factor (VEGF), keratinocyte growth factor, and insulin-like growth factor-1 (IGF-1) in the group treated with the extracts. Histological examination showed that the induction of the anagen stage of hair follicles was faster in the group treated with the extracts than in the control group. No skin irritation was observed after exposure for 24 or 72 hours. The study concluded that Lycopersicon esculentum extracts promote hair growth and could be used in hair loss treatments without causing skin irritation at moderate doses.

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