June 2025 in “Dermatologic Surgery” This study found that growth factor concentrate provides quicker improvements for patterned hair loss, but platelet-rich plasma offers more sustained benefits after treatment.
This review concludes that platelet-rich plasma is a promising treatment for androgenetic alopecia, enhancing hair density and thickness, though outcomes vary due to differences in preparation and application methods.
October 2024 in “A I Burnasyan Federal Medical Biophysical Center Clinical Bulletin” This literature review on androgenetic alopecia highlights its significant impact on patients' mental health and quality of life and discusses various treatment pathways, including topical, systemic, and surgical interventions, while emphasizing the need for continued research to develop effective therapies.
August 2024 in “Scholars Journal of Applied Medical Sciences” This study found that combining platelet-rich plasma therapy with minoxidil significantly improved hair growth and hair follicle cell proliferation in men with androgenetic alopecia compared to either treatment alone.
August 2024 in “Journal of Cosmetic Dermatology” This study reported significant improvements in hair density and growth ratio in androgenetic alopecia patients receiving concentrated growth factor injections, with benefits sustained for 6 months.
August 2024 in “Quality in Sport” This review article examines the latest understanding of androgenetic alopecia's causes and treatment options, emphasizing current research on alternative treatments beyond the approved medications, finasteride and minoxidil, due to potential side effects and the psychological impact of the condition.
May 2024 in “Indian Journal of Dermatology” In this review, an association was reported between early-onset androgenetic alopecia and several health conditions like obesity and cardiovascular disease, with genetic and therapeutic research ongoing to improve treatment.
April 2024 in “MRIMS journal of health sciences” This study observed that autologous growth factor concentrate combined with topical minoxidil significantly improved hair growth and patient satisfaction in individuals with androgenic alopecia, with no adverse effects reported.
January 2024 in “Skin appendage disorders” This research highlights that various environmental pollutants, including particulate matter, tobacco smoke, and heavy metals, can significantly affect hair follicle health, linking them to conditions like alopecia areata and androgenetic alopecia, underscoring the need for further study in this area.
July 2023 in “International journal of trichology” This review concluded that the double-spin PRP preparation method may be more effective than the single-spin technique for treating androgenetic alopecia.
May 2023 in “International Journal of Trichology” This expert consensus discusses the potential use of oral minoxidil for treating alopecia and provides guidance to clinicians based on a comprehensive literature review and expert feedback; it reports no new clinical results.
February 2023 in “Journal of Dermatological Treatment” In this study, both platelet-rich plasma and minoxidil increased hair counts and density in moderate androgenetic alopecia in men, but patient satisfaction was higher with minoxidil, which also had fewer side effects.
December 2022 in “International Journal of Research in Dermatology” This pilot study found that growth factor concentrate therapy improved hair growth in patients with androgenetic alopecia, was well tolerated, and achieved high patient satisfaction.
December 2022 in “Plastic and Reconstructive Surgery” This study found that autologous platelet-rich plasma significantly improved hair follicle number, thickness, and density in patients with androgenic alopecia compared to placebo, with high reported patient satisfaction.
1 citations
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June 2021 in “Singapore Medical Journal” This study suggests that type I 5-alpha reductase may also play a role in hair growth, with dutasteride potentially being more potent than finasteride in modulating key hair growth gene expressions.
4 citations
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August 2020 in “Facial plastic surgery & aesthetic medicine” This study found that combining concentrated growth factor injections with minoxidil treatment significantly improved hair growth and participant satisfaction in male patients with androgenetic alopecia compared to minoxidil alone.
9 citations
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October 2018 in “Medical Science Monitor” In this study, oral finasteride therapy was associated with decreased DHT levels and improved hair loss severity in young male AGA patients, while hormonal changes influenced the curative effect.
29 citations
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August 2017 in “Skin appendage disorders” This study found that IGF-1 likely plays a crucial role in regulating hair growth and alopecia, with balding scalp follicles secreting less IGF-1 than nonbalding counterparts.
43 citations
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January 2016 in “Cellular physiology and biochemistry” This study reports that EGF at specific concentrations promotes the proliferation and migration of hair follicle ORS cells by activating the Wnt/β-catenin signaling pathway in vitro.
74 citations
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January 2013 in “Journal of Investigative Dermatology” Four genetic risk spots found for hair loss, with WNT signaling involved and a link to curly hair.
151 citations
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August 2010 in “British Journal of Dermatology” This guideline reviews the diagnosis of androgenetic alopecia and offers expert consensus recommendations tailored to males, females, and adolescents, but reports no new clinical results.
269 citations
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August 2002 in “Journal of The American Academy of Dermatology” This study found that 5% topical minoxidil significantly increased hair regrowth and improved psychosocial perceptions of hair loss in men with androgenetic alopecia compared to 2% topical minoxidil and placebo over 48 weeks.
