Role of LncRNA MRPS28 in Secondary Hair Follicle Development of Cashmere Goats

    June 2025 in “ Animals ”
    Youjun Rong, Rong Ma, Qing Ma … Yanjun Zhang
    Studysummary This study in cashmere goats identified the lncRNA MRPS28, which interferes with secondary hair follicle morphogenesis by inhibiting dermal papilla formation through sponging chi-miR-145-5p, offering insights into breeding strategies for improved cashmere quality.
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    Research cited in this study 8

    1. MiR-133a-3p and MiR-145-5p Co-Promote Goat Hair Follicle Stem Cell Differentiation by Regulating NANOG and SOX9 Expression Animal Bioscience · 2023
    2. Expression Profile of Long Non-Coding RNA in Inner Mongolian Cashmere Goat With Putative Roles in Hair Follicles Development Frontiers in veterinary science · 2022
    3. Comprehensive Transcriptome Analysis of Hair Follicle Morphogenesis Reveals That lncRNA-H19 Promotes Dermal Papilla Cell Proliferation Through the Chi-miR-214-3p/Beta-Catenin Axis in Cashmere Goats International journal of molecular sciences · 2022
    4. miR-29a-5p Inhibits Prenatal Hair Placode Formation Through Targeting EDAR by ceRNA Regulatory Network Frontiers in Cell and Developmental Biology · 2022
    5. Skin Transcriptome Profiling of Changthangi Goats Highlights the Relevance of Genes Involved in Pashmina Production Scientific reports · 2020
    6. LncRNA-XIST Promotes Dermal Papilla Induced Hair Follicle Regeneration by Targeting miR-424 to Activate Hedgehog Signaling Cellular Signalling · 2020
    7. Expression of Fox-Related Genes in the Skin Follicles of Inner Mongolia Cashmere Goat Asian-Australasian journal of animal sciences · 2017
    8. Comparative Transcriptome Analysis of Fetal Skin Reveals Key Genes Related to Hair Follicle Morphogenesis in Cashmere Goats PLoS ONE · 2016

    Related research 6

    1. Single-Cell Sequencing Reveals the New Existence Form of Dermal Papilla Cells in the Hair Follicle Regeneration of Cashmere Goats Genomics · 2022
    2. Shedding Light on Cashmere Goat Hair Follicle Biology: From Morphology Analyses to Transcriptomic Landscape BMC genomics · 2020
    3. Skin Transcriptome Reveals the Periodic Changes in Genes Underlying Hair Follicle Cycling in Cashmere Goats Research Square (Research Square) · 2019
    4. Hair Follicle Transcriptome Profiles During the Transition from Anagen to Catagen in Cashmere Goat (Capra Hircus) Genetics and molecular research · 2015
    5. Exploring Differentially Expressed Genes by RNA-Seq in Cashmere Goat Skin During Hair Follicle Development and Cycling PloS one · 2013
    6. Hoxc13/β-Catenin Correlation with Hair Follicle Activity in Cashmere Goat Journal of integrative agriculture/Journal of Integrative Agriculture · 2012