Impaired Differentiation Potential of CD34-Positive Cells Derived from Mouse Hair Follicles After Long-Term Culture

    June 2022 in “ Scientific reports ”
    Yukiteru Ouji, Masayasu Misu, Tomotaka Kitamura … Masahide Yoshikawa
    Studysummary In this study, one type of commercial culture medium supported expression of stem cell markers in hair follicle epithelial stem cells, but their differentiation potential and hair follicle-inducing ability declined over time.
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    Research cited in this study 21

    1. Nanoscale Microenvironment Engineering for Expanding Human Hair Follicle Stem Cells and Revealing Their Plasticity Journal of Nanobiotechnology · 2021
    2. Expansion And Characterization Of Epithelial Stem Cells With Potential For Cyclical Hair Regeneration Scientific Reports · 2021
    3. An Intrinsic Oscillation of Gene Networks Inside Hair Follicle Stem Cells: An Additional Layer That Can Modulate Hair Stem Cell Activities Frontiers in Cell and Developmental Biology · 2020
    4. Roles of Wnt7a in Embryo Development, Tissue Homeostasis, and Human Diseases Journal of Cellular Biochemistry · 2019
    5. Isolation of Stem Cells and Progenitors from Mouse Epidermis Current Protocols in Stem Cell Biology · 2017
    6. Hair Follicle Stem Cell Proliferation, Akt and Wnt Signaling Activation in TPA-Induced Hair Regeneration Histochemistry and Cell Biology · 2017
    7. Hair Follicle Stem Cell Cultures Reveal Self-Organizing Plasticity of Stem Cells and Their Progeny The EMBO Journal · 2016
    8. Hair Follicle and Sebaceous Gland De Novo Regeneration With Cultured Epidermal Stem Cells and Skin-Derived Precursors Stem Cells Translational Medicine · 2016
    9. Mapping the Expression of Epithelial Hair Follicle Stem Cell-Related Transcription Factors LHX2 and SOX9 in the Human Hair Follicle Experimental Dermatology · 2015
    10. Markers of Epidermal Stem Cell Subpopulations in Adult Mammalian Skin Cold Spring Harbor Perspectives in Medicine · 2014
    11. Human Induced Pluripotent Stem Cell-Derived Ectodermal Precursor Cells Contribute to Hair Follicle Morphogenesis In Vivo ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2013
    12. Competitive Balance of Intrabulge BMP/Wnt Signaling Reveals a Robust Gene Network Ruling Stem Cell Homeostasis and Cyclic Activation Proceedings of the National Academy of Sciences · 2013
    13. Epithelial Stem Cells And Implications For Wound Repair Seminars in Cell & Developmental Biology · 2012
    14. Epidermal Homeostasis: A Balancing Act of Stem Cells in the Skin Nature Reviews Molecular Cell Biology · 2009
    15. Building Epithelial Tissues From Skin Stem Cells Cold Spring Harbor Symposia on Quantitative Biology · 2008
    16. The Cell-Surface Marker MTS24 Identifies a Novel Population of Follicular Keratinocytes With Characteristics of Progenitor Cells Development · 2006
    17. Wnt-10b Promotes Differentiation of Skin Epithelial Cells In Vitro Biochemical and Biophysical Research Communications · 2006
    18. Stem Cells in the Hair Follicle Bulge Contribute to Wound Repair but Not to Homeostasis of the Epidermis Nature Medicine · 2005
    19. Enrichment for Living Murine Keratinocytes from the Hair Follicle Bulge with the Cell Surface Marker CD34 Journal of Investigative Dermatology · 2003
    20. Morphogenesis and Renewal of Hair Follicles from Adult Multipotent Stem Cells Cell · 2001
    21. Involvement of Follicular Stem Cells in Forming Not Only the Follicle but Also the Epidermis Cell · 2000

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