Isoalantolactone Stimulates Hair Cell Growth Through Activation of the WNT/β-Catenin and Ras/MAPK Pathways

    June 2025 in “ Korean Journal of Pharmacognosy ”
    Bu Young Choi
    Studysummary In a mouse model, this study reported that the compound isoalantolactone significantly improved hair growth and thickness, suggesting its potential as a treatment for hair loss.
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    Research cited in this study 15

    1. Hair Growth-Promotion Effects at the Cellular Level and Antioxidant Activity of the Plant-Based Extract Phyllotex Heliyon · 2021
    2. Hair Growth Stimulation Effect of Centipeda Minima Extract: Identification of Active Compounds and Anagen-Activating Signaling Pathways Biomolecules · 2021
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    7. Costunolide Promotes the Proliferation of Human Hair Follicle Dermal Papilla Cells and Induces Hair Growth in C57BL/6 Mice Journal of Cosmetic Dermatology · 2018
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    15. Two Distinct Signaling Pathways in Hair Cycle Induction: Stat3-Dependent and Independent Pathways Proceedings of the National Academy of Sciences of the United States of America · 2000