Investigation of the Gene Expression Levels of 5 Alpha-Reductase, VEGF, and IL-1 Alpha in HaCaT Cells After the Application of a Botanical Extract

    Ahu Izgi, Murat Türkoğlu, Berrin Akyıldırım … Nuray Çelik
    Studysummary In this study, a plant extract from Northeastern Turkey demonstrated potential for preventing hair loss by downregulating inflammation and androgen production and promoting hair growth in HaCaT cell models.
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    Research cited in this study 15

    1. Hair Cycle Resting Phase Is Regulated by Cyclic Epithelial FGF18 Signaling Journal of Investigative Dermatology · 2012
    2. Progress in Relevant Growth Factors Promoting the Growth of Hair Follicles American Journal of Animal and Veterinary Sciences · 2012
    3. Review of Hair Follicle Dermal Cells Journal of Dermatological Science · 2009
    4. The Mesenchymal Component of Hair Follicle Neogenesis: Background, Methods, and Molecular Characterization Experimental Dermatology · 2009
    5. The Additive Effects of Minoxidil and Retinol on Human Hair Growth In Vitro Biological & Pharmaceutical Bulletin · 2007
    6. Epidermal Growth Factor as a Biological Switch in Hair Growth Cycle Journal of biological chemistry/˜The œJournal of biological chemistry · 2003
    7. Plasticity and Cytokinetic Dynamics of the Hair Follicle Mesenchyme During the Hair Growth Cycle: Implications for Growth Control and Hair Follicle Transformations ˜The œjournal of investigative dermatology. Symposium proceedings/˜The œJournal of investigative dermatology symposium proceedings · 2003
    8. Androgenetic Alopecia: Pathogenesis and Potential for Therapy Expert Reviews in Molecular Medicine · 2002
    9. Androgenetic Alopecia in Men and Women Clinics in Dermatology · 2001
    10. Current Understanding of Androgenetic Alopecia: Part I - Etiopathogenesis PubMed · 2000
    11. Evidence of Heterogeneity and Quantitative Differences of the Type 1 5α-Reductase Expression in Cultured Human Skin Cells: Evidence of Its Presence in Melanocytes Journal of Investigative Dermatology · 1998
    12. The Control of Hair Growth: An Overview Journal of Investigative Dermatology · 1993
    13. The Secret Life of the Hair Follicle Trends in genetics · 1992
    14. Acidic and Basic Hair/Nail (Hard) Keratins: Their Colocalization in Upper Cortical and Cuticle Cells of the Human Hair Follicle and Their Relationship to Soft Keratins ˜The œjournal of cell biology/˜The œJournal of cell biology · 1986
    15. Growth of the Hair Physiological Reviews · 1954