Frontal Fibrosing Alopecia: An Observational Single-Center Study of 306 Cases

    June 2023 in “ Life
    Marcos Carmona‐Rodríguez, Fernando Moro‐Bolado, G. Romero-Aguilera, Ricardo Ruiz‐Villaverde, Víctor Carriel
    Image of study
    TLDR The study concluded that Frontal fibrosing alopecia can affect younger people, is often missed in men, and may be autoimmune-related.
    The observational study conducted at the Hospital General Universitario in Ciudad Real, Spain, analyzed 306 patients diagnosed with Frontal fibrosing alopecia (FFA) from 2010 to 2021. The severity of FFA was found to correlate with the time of progression. Hypothyroidism was present in 22.9% of patients, and signs of lichen planopilaris were observed in 9.8% of patients. The study also found that 27.2% of patients had androgenetic alopecia, 21.5% had facial papules, and 63.3% experienced itching. Inflammatory signs were seen in 67.3% and 61.4% of patients, but these were not associated with disease severity. The study concluded that FFA may affect younger patients and is likely underdiagnosed in males, and suggested that an autoimmune mechanism may be involved in the pathogenesis of FFA.
    Discuss this study in the Community →

    Research cited in this study

    28 / 28 results

    Related Community Posts Join

    6 / 393 results

      community Testosterone and hair loss seeming irrelevance

      in Research/Science  81 upvotes 1 year ago
      The conversation is about the role of testosterone in hair loss and the effectiveness of different treatments. The conclusion is that DHT is the main culprit for hair loss, and finasteride has been proven to work long-term in maintaining and regrowing hair. Testosterone may have a minor effect, but it is not the primary cause of hair loss.
      Diffuse hair loss and scalp biopsies

      community Diffuse hair loss and scalp biopsies

      in Research  692 upvotes 4 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community 9 months on Fin - no progress , should I get on Dutasteride?

      in Chat  10 upvotes 1 month ago
      The user has been using finasteride, minoxidil, and nizoral for hair loss but hasn't seen regrowth, only maintenance. They are considering switching to dutasteride, which is believed to be more effective, but are concerned about potential side effects.

      community Diffuse thinning is so brutal.

      in Styling  72 upvotes 1 year ago
      A 25-year-old with AGA experienced hair thinning and dandruff, stabilized with topical finasteride and minoxidil but saw minimal regrowth. They seek advice on styling and consider oral minoxidil and microneedling for denser hair.

      community scarring alopecia awareness in this community

      in Chat  33 upvotes 2 years ago
      Lichen Planopilaris (LPP), a form of permanent hair loss, which can be mistaken for seborrheic dermatitis and is characterized by scalp itching, burning, redness, and dandruff. Treatment options discussed include steroidal creams, finasteride, minoxidil, and RU58841.

    Similar Research

    6 / 1000+ results