Exosomes and Hair Restoration

March 2023 in “ Advances in Cosmetic Surgery ”

Aditya K. Gupta, Deanna C. Hall, Jeffrey A. Rapaport, Christopher R. Paradise

exosomes hair follicle hair growth regulation hair regeneration molecular signals proteins mRNAs microRNAs

TLDR Exosomes, tiny cell-released particles, may help hair growth, but their exact role is unclear, they're not FDA-approved, and their unregulated use can cause side effects.

Exosomes are small vesicles released by cells that contain proteins, mRNAs, and microRNAs. They have been found to play a role in hair growth by delivering molecular signals to hair follicle components and interacting with molecules involved in hair growth regulation. However, the specific effects of exosomes on hair regeneration are not fully understood and may vary depending on their source. Currently, there are no FDA-approved exosome therapies for hair growth and regeneration, and caution is advised due to reports of adverse effects from unregulated use. More controlled human clinical research is needed to determine the effectiveness and safety of exosomes for hair restoration.

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Research cited in this study

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research Immunoregulatory Effects of Myeloid-Derived Suppressor Cell Exosomes in Mouse Model of Autoimmune Alopecia Areata

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