Extremely Low-Frequency Electromagnetic Fields Increase the Expression of Anagen-Related Molecules in Human Dermal Papilla Cells via GSK-3β/ERK/Akt Signaling Pathway

    Ga-Eun Ki, Yumi Kim, Han-Moi Lim, Eun-Cheol Lee, Yun-Kyong Choi, Young-Kwon Seo
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    TLDR Low-frequency electromagnetic fields can boost molecules related to hair growth in human skin cells.
    In January 2020, a study was conducted to investigate the effects of Extremely Low-Frequency Electromagnetic Fields (ELF-EMFs) on human Dermal Papilla Cells (hDPCs), which are crucial for hair growth. The researchers exposed hDPCs to ELF-EMFs at a frequency of 70 Hz and intensities ranging from 5 to 100 G over four days. The results showed that ELF-EMFs significantly increased the expression of anagen-related molecules, with an intensity of 10 G being the most effective for promoting hDPC proliferation. The study concluded that ELF-EMFs enhance hDPC activation and proliferation via the GSK-3β/ERK/Akt signaling pathway, suggesting a potential treatment strategy for alopecia. However, further studies on human hair follicle organ culture or in vivo studies were recommended. The number of participants in the study was not mentioned.
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