Effects of Taxifolin From Enzymatic Hydrolysis of Rhododendron Mucronulatum on Hair Growth Promotion

    September 2022 in “ Frontiers in Bioengineering and Biotechnology ”
    Sunmin Park, Yi-Chang He, Chun Gong … Sun-Eun Choi
    Studysummary This study reports that taxifolin from enzymatic hydrolysis effectively regulates dermal papilla cell apoptosis and promotes hair growth by increasing IGF-1 and reducing TGF-β1, though it shows less inhibition of DHT compared to minoxidil.
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    Research cited in this study 16

    1. Application of Ethanol Extracts From Alnus Sibirica Fisch. ex Turcz in Hair Growth Promotion Frontiers in Bioengineering and Biotechnology · 2021
    2. Safety of Low-Dose Oral Minoxidil Treatment for Hair Loss: A Systematic Review and Pooled Analysis of Individual Patient Data Dermatologic Therapy · 2020
    3. An Overview of Herbal Alternatives in Androgenetic Alopecia Journal of Cosmetic Dermatology · 2019
    4. TGFβ Family Mimetic Peptide Promotes Proliferation of Human Hair Follicle Dermal Papilla Cells and Hair Growth in C57BL/6 Mice Biomedical dermatology · 2018
    5. Aging, Alopecia, and Stem Cells Science · 2016
    6. Induction of Transforming Growth Factor-Beta 1 by Androgen Is Mediated by Reactive Oxygen Species in Hair Follicle Dermal Papilla Cells Journal of Biochemistry and Molecular Biology · 2013
    7. Androgens and Hair Growth Dermatologic Therapy · 2008
    8. Topical Use of Minoxidil in Children and Systemic Side Effects Dermatology · 2007
    9. The Importance of Dual 5α-Reductase Inhibition in the Treatment of Male Pattern Hair Loss: Results of a Randomized Placebo-Controlled Study of Dutasteride Versus Finasteride Journal of The American Academy of Dermatology · 2006
    10. Positive Lymphocyte Transformation Test in a Patient with Allergic Contact Dermatitis of the Scalp After Short-Term Use of Topical Minoxidil Solution Contact Dermatitis · 2005
    11. Identification of Androgen-Inducible TGF-β1 Derived from Dermal Papilla Cells as a Key Mediator in Androgenetic Alopecia Journal of Investigative Dermatology Symposium Proceedings · 2003
    12. Pseudoacromegaly Induced by the Long-Term Use of Minoxidil Journal of The American Academy of Dermatology · 2003
    13. Androgens and Alopecia Molecular and Cellular Endocrinology · 2002
    14. Molecular Mechanisms of Androgenetic Alopecia Experimental Gerontology · 2002
    15. Treatment of Hair Loss The New England Journal of Medicine · 1999
    16. Age Dependence of the Cardiac Lesions Induced by Minoxidil in Rats Toxicology · 1996