A Stability Indicating UPLC Method for Finasteride and Its Related Impurities

    January 2012 in “ American Journal of Analytical Chemistry ”
    Y. V. Rami Reddy, G.V. Prasad Reddy, K. N. Jaya Veera, Kishore Kumar Hotha
    Studysummary This study developed and validated a gradient reversed-phase liquid chromatographic method to effectively measure Finasteride and its related impurities in pharmaceutical bulk drugs, demonstrating high linearity and precision.
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    Research cited in this study 13

    1. Bioequivalence Study of Finasteride Drug Research · 2011
    2. Bioequivalence Study of Two Different Coated Tablet Formulations of Finasteride in Healthy Volunteers Drug Research · 2011
    3. Rapid Determination of Finasteride in Human Plasma by UPLC-MS/MS and Its Application to Clinical Pharmacokinetic Study Journal of Chromatography B · 2010
    4. A Rapid, Simple, Specific Liquid Chromatographic–Electrospray Mass Spectrometry Method for the Determination of Finasteride in Human Plasma and Its Application to Pharmacokinetic Study Journal of Pharmaceutical and Biomedical Analysis · 2006
    5. A New Spectrophotometric Method for the Determination of Finasteride in Tablets Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy · 2006
    6. Polarographic Behavior and Determination of Finasteride Farmaco · 2003
    7. Separation of Finasteride and Analogues Journal of Chromatography B: Biomedical Sciences and Applications · 2001
    8. Determination of Finasteride in Human Plasma by Liquid-Liquid Extraction and High-Performance Liquid Chromatography Journal of Chromatography B: Biomedical Sciences and Applications · 2000
    9. Matrix Effect in Quantitative LC/MS/MS Analyses of Biological Fluids: A Method for Determination of Finasteride in Human Plasma at Picogram Per Milliliter Concentrations Analytical Chemistry · 1998
    10. Finasteride in Biological Fluids: Extraction and Separation by a Graphitized Carbon Black Cartridge and Quantification by High-Performance Liquid Chromatography Journal of Chromatography B: Biomedical Sciences and Applications · 1997
    11. High-Performance Liquid Chromatographic Determination of Finasteride in Human Plasma Using Direct Injection with Column Switching Journal of Chromatography B: Biomedical Sciences and Applications · 1996
    12. Synthesis of 5,6,6-[2H3]Finasteride and Quantitative Determination of Finasteride in Human Plasma at Picogram Level by an Isotope-Dilution Mass Spectrometric Method Journal of Chromatography B: Biomedical Sciences and Applications · 1995
    13. Picogram Determination of Finasteride in Human Plasma and Semen by High-Performance Liquid Chromatography with Atmospheric-Pressure Chemical-Ionization Tandem Mass Spectrometry Journal of Chromatography B: Biomedical Sciences and Applications · 1994