Cyproterone Acetate-Loaded Nanostructured Lipid Carriers: Effect of Particle Size on Skin Penetration and Follicular Targeting

    March 2019 in “ Pharmaceutical development and technology ”
    Parisa Ghasemiyeh, Amir Azadi, Saeid Daneshamouz … Soliman Mohammadi-Samani
    Studysummary The study found that cyproterone acetate-loaded nanostructured lipid carriers, particularly those with a 300 nm diameter, improved skin penetration and targeted hair follicles more effectively than free cyproterone acetate.
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    Research cited in this study 13

    1. Development and Optimization of Spironolactone Nanoparticles for Enhanced Dissolution Rates and Stability Aaps Pharmscitech · 2016
    2. The Effect of Particle Size on the Deposition of Solid Lipid Nanoparticles in Different Skin Layers: A Histological Study Advanced Pharmaceutical Bulletin · 2016
    3. Roxithromycin-Loaded Lipid Nanoparticles for Follicular Targeting International Journal of Pharmaceutics · 2015
    4. Applications and Limitations of Lipid Nanoparticles in Dermal and Transdermal Drug Delivery via the Follicular Route European journal of pharmaceutics and biopharmaceutics · 2015
    5. Improved Poly (D,L-Lactide) Nanoparticles-Based Formulation for Hair Follicle Targeting International Journal of Cosmetic Science · 2015
    6. Comparison of Rheological Properties, Follicular Penetration, Drug Release, and Permeation Behavior of a Novel Topical Drug Delivery System and a Conventional Cream European journal of pharmaceutics and biopharmaceutics · 2014
    7. Topical Formulations Containing Finasteride: In Vitro Permeation/Penetration Study and In Vivo Pharmacokinetics in Hairless Rat Journal of Pharmaceutical Sciences · 2014
    8. Topical Formulations Containing Finasteride: Determination of Finasteride Penetration into Hair Follicles Using the Differential Stripping Technique Journal of Pharmaceutical Sciences · 2014
    9. Solid Lipid Nanoparticles: Method, Characterization, and Applications International Current Pharmaceutical Journal · 2012
    10. Hair Follicle Targeting with Nanoparticles Springer eBooks · 2012
    11. Selective Follicular Targeting by Modification of the Particle Sizes Journal of Controlled Release · 2011
    12. Determination of the Cuticle Thickness of Human and Porcine Hairs and Their Potential Influence on the Penetration of Nanoparticles into the Hair Follicles Journal of Biomedical Optics · 2009
    13. Penetration Profile of Microspheres in Follicular Targeting of Terminal Hair Follicles ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2004