MiR-199a-3p Regulates the PTPRF/β-Catenin Axis in Hair Follicle Development: Insights into the Pathogenic Mechanism of Alopecia Areata

    December 2023 in “ International journal of molecular sciences ”
    Jiankui Wang, Yuhao Ma, Tun Li … Xing‐Wang Deng
    Studysummary In this study, researchers found that miR-199a-3p plays a regulatory role in hair follicle development via the PTPRF/β-catenin axis and established a mouse model of alopecia areata by downregulating this small RNA, suggesting its potential value in studying alopecia diseases.
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    Research cited in this study 20

    1. Baricitinib as the First Systemic Treatment for Severe Alopecia Areata Expert Review of Clinical Immunology · 2023
    2. Quality of Life in Children and Adolescents With Alopecia Areata: A Systematic Review Journal of the European Academy of Dermatology and Venereology · 2023
    3. Factors Influencing Alopecia Areata Treatment Decisions: A Qualitative Assessment JAAD International · 2022
    4. Evaluation of the Level of Serum Interleukins (IL-2, IL-4, IL-15, and IL-17) and Its Relationship with Disease Severity in Patients with Alopecia Areata Anais brasileiros de dermatologia/Anais Brasileiros de Dermatologia · 2021
    5. Alopecia Areata: An Autoimmune Disease of Multiple Players ImmunoTargets and therapy · 2021
    6. Alopecia Areata in a Patient with WNT10A Heterozygous Ectodermal Dysplasia Dermatology Online Journal · 2021
    7. Treatment of Pediatric Alopecia Areata: A Systematic Review Journal of the American Academy of Dermatology · 2021
    8. Alopecia Areata: A Review on Diagnosis, Immunological Etiopathogenesis, and Treatment Options Clinical and Experimental Medicine · 2021
    9. Utility of Azathioprine, Methotrexate, and Cyclosporine as Steroid-Sparing Agents in Chronic Alopecia Areata: A Retrospective Study of Continuation Rates in 138 Patients JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology · 2020
    10. Psychosomatic Aspects of Alopecia Areata Clinics in Dermatology · 2018
    11. Alopecia Areata: A Review of Disease Pathogenesis British journal of dermatology/British journal of dermatology, Supplement · 2018
    12. Assessment of Tissue Levels of Dickkopf-1 in Androgenetic Alopecia and Alopecia Areata Journal of Cosmetic Dermatology · 2015
    13. Genetic Basis of Alopecia Areata Dermatologic clinics · 2012
    14. Medical and Environmental Risk Factors for the Development of Central Centrifugal Cicatricial Alopecia Archives of Dermatology · 2011
    15. Environmental Stress But Not Subjective Distress in Children or Adolescents With Alopecia Areata Journal of psychosomatic research · 2011
    16. Peripheral Blood Gene Expression in Alopecia Areata Reveals Molecular Pathways Distinguishing Heritability, Disease, and Severity Genes and Immunity · 2010
    17. Clinical Significance of Dermoscopy in Alopecia Areata: Analysis of 300 Cases International Journal of Dermatology · 2008
    18. Wnt-Dependent De Novo Hair Follicle Regeneration in Adult Mouse Skin After Wounding Nature · 2007
    19. Alopecia Areata: Treatment of Today and Tomorrow Journal of Investigative Dermatology Symposium Proceedings · 2003
    20. Molecular Mechanisms Regulating Hair Follicle Development ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2002

    Related research 4

    1. Alopecia Areata: A Multifactorial Autoimmune Condition Journal of autoimmunity · 2018
    2. Linear Alopecia Areata JAAD case reports · 2018
    3. Treating Resistant Cases of Alopecia Universalis Journal of cosmetology & trichology · 2018
    4. Trans-Species Hair Growth Induction by Human Hair Follicle Dermal Papillae Experimental Dermatology · 2001