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    Linking Diet to Acne Metabolomics, Inflammation, and Comedogenesis: An Update

    July 2015 in “ Clinical, Cosmetic and Investigational Dermatology ”
    Bodo C. Melnik
    Studysummary This review discusses how Western diet may contribute to acne vulgaris through insulin signaling and metabolomic changes, promoting a dietary approach for management, but reports no new experimental results.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 12

    1. TGFβ Signaling Regulates Lipogenesis in Human Sebaceous Gland Cells BMC Dermatology · 2013
    2. Androgen Actions on the Human Hair Follicle: Perspectives Experimental Dermatology · 2012
    3. The Role of Androgen and Androgen Receptor in Skin-Related Disorders Archives of Dermatological Research · 2012
    4. Acne-Associated Syndromes: Models for Better Understanding of Acne Pathogenesis Journal of The European Academy of Dermatology and Venereology · 2010
    5. Sebum Free Fatty Acids Enhance the Innate Immune Defense of Human Sebocytes by Upregulating Beta-Defensin-2 Expression Journal of Investigative Dermatology · 2009
    6. Role of Insulin, Insulin-Like Growth Factor-1, Hyperglycemic Food, and Milk Consumption in the Pathogenesis of Acne Vulgaris Experimental dermatology · 2009
    7. Role of FGFR2-Signaling in the Pathogenesis of Acne Dermato-endocrinology · 2009
    8. Differentiation of the Sebaceous Gland Dermato-Endocrinology · 2009
    9. Smad7-Induced Beta-Catenin Degradation Alters Epidermal Appendage Development Developmental Cell · 2006
    10. Expression of ΔNLef1 in Mouse Epidermis Results in Differentiation of Hair Follicles into Squamous Epidermal Cysts and Formation of Skin Tumors Development · 2002
    11. Tcf3 and Lef1 Regulate Lineage Differentiation of Multipotent Stem Cells in Skin Genes & Development · 2001
    12. Androgen Receptor Polymorphisms (CAG Repeat Lengths) in Androgenetic Alopecia, Hirsutism, and Acne Journal of Cutaneous Medicine and Surgery · 1998