1 citations
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January 2009 in “X-ray Structure Analysis Online” A new compound was made that might help treat diseases related to male hormones.
13 citations
,
August 2013 in “Journal of pharmaceutical sciences” This study found that a transdermal delivery system using 3% azone and P407 gel may enhance the skin permeation of doxazosin and finasteride for treating benign prostatic hyperplasia.
December 2016 in “Journal of Pakistan Association of Dermatology” This study found that a combination of systemic cyproterone acetate, ethinyl estradiol, and 5% topical minoxidil significantly improved hair growth and prevented further hair loss in women with female pattern hair loss over six months, with the treatment being well-tolerated.
This review outlines diagnostic and treatment approaches for hirsutism, highlighting spironolactone or cyproterone acetate with oral contraceptives as the most effective therapy, and reports no new empirical results.
August 2023 in “JAAD International” This study evaluated low dose oral minoxidil as a treatment for female pattern hair loss but reports no new clinical results.
3 citations
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November 2017 in “International Journal of Pharmacy and Pharmaceutical Sciences” This study identified new oxidative derivatives of finasteride, including a newly discovered metabolite, by using the fungus Macrophomina phaseolina.
January 2026 in “International Journal of Applied Pharmaceutics” This study developed a novel LC-ESI-MS/MS method to quantify Minoxidil in pharmaceutical forms, finding it precise, accurate, and robust. It withstands excipient and degradant interference, although Minoxidil degrades under some stress conditions but remains stable thermally.
June 2026 in “Frontiers in Medicine” This study conducted a large-scale comparison using FAERS data to assess the post-marketing safety profiles of spironolactone, eplerenone, and finerenone, finding unique adverse event patterns for each drug and highlighting the need for personalized safety monitoring and further investigation in other pharmacovigilance databases.
1 citations
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July 2022 in “Han'gug sigpum yeong'yang gwahag hoeji/Journal of the Korean society of food science and nutrition” In this study, ELE was found to protect against oxidative stress-induced testosterone reduction in TM3 Leydig cells by increasing testosterone synthesis and decreasing its conversion.
6 citations
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February 2009 in “Veterinární Medicína” This study found that deslorelin implants can effectively reduce estradiol levels and support hair regrowth in neutered ferrets with hyperoestrogenism caused by nodular hyperplasia of the adrenocortex.
1 citations
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March 2013 in “The European Journal of Contraception & Reproductive Health Care” This publication discusses the political rationale behind the French regulator ANSM's decision to withdraw Diane®-35 from the market, in response to health concerns associated with third-generation oral contraceptives.
78 citations
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October 2003 in “Cochrane library” This review found that adding cyproterone acetate to estradiol showed a subjective improvement in hirsutism versus placebo, but comparisons with other therapies revealed no clinical differences.
January 1989 in “Oxford University Research Archive (ORA) (University of Oxford)” This study found that spironolactone effectively reduced hair growth in hirsute women over 12 months and was generally well tolerated.
39 citations
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August 2022 in “Pharmaceutics” This study found that the combination of letrozole and quercetin loaded in spanlastics showed enhanced cytotoxicity and other anticancer effects against MCF-7 breast cancer cells compared to individual treatments.
December 2024 in “Jurnal Syntax Admiration” This study found that MOOEW Hair Tonic had a Return of Investment of over 100%, indicating significant potential for profitable and sustainable business opportunities.
14 citations
,
August 2007 in “Bioorganic & Medicinal Chemistry Letters” This study reported that the compound (1R, 2S)-4-(2-cyano-cyclohexyl-oxy)-2-trifluoromethyl-benzonitrile effectively stimulated hair growth in mice and reduced sebum production in hamsters.
September 2024 in “Journal of Cosmetic Dermatology” This study examined the FDA Adverse Event Reporting System database and found significant associations between low-dose oral minoxidil use and adverse events like pericardial effusion, highlighting the need for caution and recommending the use of the lowest effective dose until more safety data are available.
47 citations
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September 2013 in “Aaps Pharmscitech” This study found that liquid crystalline nanoparticles formulated with Cremophor surfactants significantly enhanced skin permeation of finasteride compared to lower surfactant concentrations.
September 2022 in “Pharmacy Today”
September 2024 in “Journal of the American Academy of Dermatology” This review discusses the consensus reached by international experts on guidelines for prescribing and monitoring low-dose oral minoxidil for hair loss, and reports no new clinical results.
25 citations
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October 2019 in “Journal of Endocrinological Investigation” This study reported that both drospirenone and chlormadinone acetate oral contraceptives had similar beneficial effects on clinical, metabolic, and hormonal parameters in women with polycystic ovary syndrome over six months.
127 citations
,
June 2006 in “International Journal of Pharmaceutics” This research found that liquid-state liposomes and niosomes may enhance finasteride delivery to pilosebaceous units in hamsters more effectively than gel-state vesicles or hydroalcoholic solution.
1 citations
,
December 1970 in “European journal of endocrinology” This study reports experience treating 140 women with hirsutism and other virilism signs using cyproterone acetate and ethinyl estradiol, focusing on those treated for over five months.
1 citations
,
March 2009 in “The Journal of Urology” This review discusses trials on therapies for benign prostatic hyperplasia and reports that combination treatment is more effective than monotherapy for symptom relief and slowing disease progression in men with moderate to severe symptoms and enlarged prostate glands.
April 2024 in “Dermatology The American Medical Journal” This study developed expert consensus guidelines on the safe and effective prescription of low-dose oral minoxidil for treating hair loss by engaging 43 dermatologists from 12 countries in a structured Delphi process, yielding 78 consensus items on safety, efficacy, dosing, and monitoring.
6 citations
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May 2024 in “PLoS ONE” In this study, content analysis of German YouTube videos revealed that women frequently experience both positive and negative symptoms related to oral contraceptive use and discontinuation, with bodily sensations often influencing their decisions to start or stop the pill.
September 2020 in “Scientific periodicals of Ukraine” This study found that the combination therapy of Flosin and Prostamol Uno over nine years was well tolerated and equally effective in managing benign prostatic hyperplasia symptoms as the combination of doxazosin and finasteride, with fewer adverse events reported.
April 2026 in “The Journal of Steroid Biochemistry and Molecular Biology”
80 citations
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December 2017 in “International Journal of Dermatology” This study reported that once-daily treatment with oral minoxidil and spironolactone for 12 months reduced hair loss severity and hair shedding in women with pattern hair loss, with generally mild side effects, though results came from an uncontrolled, observational pilot study.
Media coverage led to more dermatologists prescribing low-dose oral minoxidil for hair loss.