research Sex Hormones and Sarcopenia in Older Persons
Sex hormone treatments can increase muscle mass in older adults but have inconsistent effects on muscle function and may carry cardiovascular risks.
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research Over-Expression of Thymosin Beta4 Promotes Abnormal Tooth Development and Stimulation of Hair Growth
Too much thymosin beta4 causes weird teeth and more hair growth in mice.
research Keratin Formation in the Hair Follicle
Keratin fibrils in hair form and stop growing at specific points in the follicle.
research Transdermal Finasteride Delivery via Powder-Carrying Microneedles with a Diffusion Enhancer to Treat Androgenetic Alopecia
Microneedles with enhancer effectively promote hair growth and increase hair density.
research Minoxidil Stimulates Elastin Expression in Aortic Smooth Muscle Cells
research FOXN1 Deficient Nude Severe Combined Immunodeficiency
FOXN1 gene mutations cause a rare, severe immune disease treatable with cell or tissue transplants.
research Oral Syphilis: Report of Three Cases and Characterization of the Inflammatory Cells
The document concludes that recognizing oral lesions is important for diagnosing syphilis.
research Human FOXN1 Deficiency Is Associated with Alpha Beta Double-Negative and FoxP3 Positive T-Cell Expansions That Are Distinctly Modulated upon Thymic Transplantation
Thymic transplantation normalized some T-cells but not others, maintaining immune function.
research Telogen Effluvium: Acute and Chronic Hair Loss Conditions
Telogen effluvium is a hair loss condition with acute cases resolving quickly and chronic cases potentially lasting longer, sometimes requiring treatment.
research Cutaneous Lesions in Systemic Lupus Erythematosus
Skin problems are common in lupus, important for diagnosis, and can be triggered by sunlight.
research Hair-Root Adaptation to Marasmus in Andean Indian Children
Children with marasmus have more resting hair follicles and thinner, less pigmented hair, showing long-term malnutrition.
research Shampoos, Conditioners, and Camouflage Techniques
Cosmetic hair products are important for hiding hair loss and improving satisfaction when combined with medical treatments.
research Structure of Human Steroid 5α-Reductase 2 with the Anti-Androgen Drug Finasteride
Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.
research In Silico Prediction of Prostaglandin D2 Synthase Inhibitors from Herbal Constituents for the Treatment of Hair Loss
Herbal compounds like ricinoleic acid, quercetin-3-O-rutinoside, and hinokiflavone may be safe and effective for treating hair loss.
research Keratinocyte Stem Cells but Not Melanocyte Stem Cells Are the Primary Target for Radiation-Induced Hair Graying
Radiation mainly affects keratinocyte stem cells, not melanocyte stem cells, causing hair to gray.
research Hair Loss in Children
Most hair loss in children is caused by a few common conditions, and it's important to diagnose these properly and support the child's mental health.
research Mechanism of TAp73 Inhibition by ΔNp63 and Structural Basis of p63/p73 Hetero-Tetramerization
ΔNp63α stops TAp73β from working in skin cancer by blocking its access to specific genes, not by directly interacting with it.
research Development, Structure, and Keratin Expression in C57BL/6J Mouse Eccrine Glands
The study found that mouse sweat glands develop before birth, mature after birth, and have specific keratin patterns.
research Drug Delivery System Based On Minoxidil Nanoparticles Promotes Hair Growth In C57BL/6 Mice
Minoxidil nanoparticles can potentially be a more effective treatment for hair growth than current treatments.
research Gender-Affirming Hormone Therapy for Transgender Men
Testosterone therapy seems safe and effective for transgender men with proper care, but more long-term research is needed.
research Resveratrol Derivatives: A Patent Review (2009–2012)
New resveratrol-related compounds show promise for treating various health issues but need more research for clinical use.
research The Rationale for Physiological Testosterone Replacement in Women
Testosterone replacement may help post-menopausal women with androgen insufficiency, but more research is needed on its benefits and risks.
research Oleic Acid Nanovesicles of Minoxidil for Enhanced Follicular Delivery
Oleic acid nanovesicles improve minoxidil absorption in hair follicles for alopecia treatment.
research Let Astaxanthin Be Thy Medicine
Astaxanthin is a safe antioxidant that may improve heart, skin, eye health, and physical performance, and help manage chronic diseases.
research An N-Ethyl-N-Nitrosourea Induced Corticotropin-Releasing Hormone Promoter Mutation Provides a Mouse Model for Endogenous Glucocorticoid Excess
Researchers created a mouse model for Cushing's syndrome to study glucocorticoid excess and potential treatments.
research Injectable Self-Healing Ceria-Based Nanocomposite Hydrogel with ROS-Scavenging Activity for Skin Wound Repair
The hydrogel speeds up skin wound healing and helps regenerate tissue.
research Treatment of Alopecia Areata in Pre-Adolescent Children with Oral Tofacitinib: A Retrospective Study
Oral tofacitinib may effectively treat hair loss in children with alopecia areata.
research Transdermal Composite Microneedle Composed of Mesoporous Iron Oxide Nanoraspberry and PVA for Androgenetic Alopecia Treatment
Microneedle made of iron oxide and PVA helps hair regrowth in alopecia treatment.
research Tannic Acid Accelerates Cutaneous Wound Healing in Rats Via Activation of the ERK 1/2 Signaling Pathways
Tannic acid helps wounds heal faster in rats by activating certain cell signals and reducing inflammation.
research Cognitive Effects of Testosterone and Finasteride Administration in Older Hypogonadal Men
Testosterone improves mood and thinking skills; finasteride has no effect.