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The review concluded that male pattern baldness is mostly seen negatively, affecting attractiveness and social appeal.

Aging in hair follicle stem cells leads to hair graying, thinning, and loss.

SOX9 helps determine stem cell roles by interacting with DNA and proteins that control gene activity.

Human sebaceous glands contain enzymes that affect androgen production and may influence sebum production and acne.

The document concludes that hair follicles have a complex environment and our understanding of it is growing, but there are limitations when applying animal study findings to humans.

Understanding hair growth involves complex factors, and more research is needed to improve treatments for hair loss conditions.

Hair damage increases significantly with higher temperatures and longer heating times.

Boys with less severe EDA mutations in XLHED have milder symptoms and better sweat and hair production.

Rare changes in the KRT82 gene are linked to a higher risk of Alopecia Areata.

Androgens affect bone and fat cell development differently based on the cells' embryonic origin.

Researchers created a mouse with the same mutation as humans with trichothiodystrophy, showing similar symptoms and confirming the condition is due to defects in DNA repair and gene activity.

Keratin-associated proteins have ancient origins and were used for different purposes before being adapted for hair in mammals.

Certain long non-coding RNAs are important for controlling hair growth cycles in sheep.

The conclusion is that proper signaling is crucial for hair growth and development, and errors can lead to cancer or hair loss.

Testosterone therapy can improve sexual desire and function in postmenopausal women but should be used cautiously and not based solely on testosterone levels.

Animal models, especially mice, are essential for advancing hair loss research and treatment.

The study provides insights into hair growth mechanisms in yaks.

Baldness and shaved heads change how traits are seen but don't really affect leader preferences.

The genes KRT25 and SP6 affect curly hair in horses, with KRT25 also causing hair loss. If both genes are mutated, the horse gets curly hair and hair loss. KRT25 can hide the effect of SP6.

Too much β-catenin activity can mess up the development of mammary glands and make them more like hair follicles.

Lysophosphatidic acid is important for skin health and disease, and could be a target for new skin disorder treatments.

Melatonin helps hair grow by activating a specific signaling pathway.

Different signals work together to change gene activity and guide hair follicle stem cells to become specific cell types.

Signaling pathways are crucial for hair growth in goats.

Pitx2 helps outer root sheath cells differentiate but can't start hair growth on its own.

Researchers found potential urine markers for polycystic ovary syndrome, including testosterone-glucuronide and 11α-hydroxyprogesterone, which may help diagnose the condition.

Valproic acid helps delay hair loss and increases survival time for high-grade glioma patients undergoing radiation therapy.

PPARγ is essential for maintaining healthy skin, controlling inflammation, and ensuring proper skin barrier function.

The Wnt signaling pathway is not a major factor in the development of keratoacanthoma, a type of skin tumor.

Researchers found markers that can tell if hair has been bleached, which could improve hair test accuracy.