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The anti-viral drug Elvitegravir may protect brain cells from damage related to neurodegenerative diseases.

Most drugs fail to reach the market, but understanding their properties and using strategies like early toxicity tests and drug repurposing can help advance their development.

Dental pulp stem cells might not reliably become neurons.

Some herbal ingredients like linalool and tea tree oil have anti-dandruff properties and are safe for use in shampoos.

Mitochondrial dysfunction is linked to various skin conditions and could be a target for treatments.

Studying rare genetic disorders can help us understand and treat common diseases better.

Osthole inhibits the TRPV3 channel by binding to specific sites, potentially aiding drug development for skin diseases and cancers.

Dogs have varying numbers of touch-sensitive Merkel cells in different skin areas, with most in the oral mucosa and facial skin, unrelated to age, sex, breed, or color.

Genetic variants can affect valproic acid's effectiveness, side effects, and levels in epilepsy treatment.

Using focused ultrasound on the brain can help epilepsy medicine work better in rats.

Not getting enough minerals can lead to health problems and shorter lifespans.

Potassium channel openers help form elastic fibers in arteries and can treat elastin deficiency and hypertension.

TRPV4 helps cells repair tissue and reduce scarring by controlling calcium levels.

The CAP1 gene helps control ammonium levels and is necessary for the proper growth of root hairs in Arabidopsis.

Minoxidil can reduce functions related to androgen receptors.

Human skin can be reconnected to nerves using stem cells, which may help with skin health and healing.

Hormones during puberty increase certain receptors in the brain, and this change is influenced by estrogen levels.

Dutasteride, usually used for prostate issues and hair loss, could potentially treat Amyotrophic Lateral Sclerosis (ALS) due to its neuroprotective, antioxidant, and anti-inflammatory properties, but more testing is needed.

Hair follicles have a more inactive cell cycle than other skin cells, which may help develop targeted therapies for skin diseases and cancer.

Low-dose oral minoxidil may help treat hair loss but is not FDA-approved and can cause side effects like unwanted hair growth and heart issues.

4-Aminopyridine improves skin wound healing and tissue regeneration by increasing cell growth and promoting nerve repair.

Olfactory receptors found outside the nose may offer new treatments for diseases like cancer and help in wound healing and hair growth.

The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.

Activating TRPV3 channels stops hair growth by killing hair follicle cells.

The conclusion is that a new test was created to find substances that affect specific ion channels, and it works well for drug discovery.

Cromakalim relaxes various blood vessels, while minoxidil sulphate is more selective; they likely act on different potassium channels.

Some common medications can harm male fertility, but many effects can be reversed.

Activating TRPV3 stops human hair growth.

Neuroactive steroids show promise for treating mental and neurological disorders by targeting GABA_A receptors.

PGD2 stops hair growth and is higher in bald men with AGA.