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This systematic review found an inverse relationship between vitamin D levels and the severity, extent, and pattern of alopecia areata, suggesting vitamin D deficiency may contribute to or worsen this autoimmune hair loss condition.

This review discusses the role of vitamin D metabolism in skin immunity and wound healing but does not present new results, highlighting the need for further research into its therapeutic applications.

This study provides evidence-based recommendations for the off-label use of topical vitamin D in treating certain skin conditions, but highlights the need for higher quality studies for further validation.

This study observed that vitamin D deficiency in alopecia areata correlates inversely with disease severity and duration, but does not correlate with serum vitamin D levels.

This study found that individuals with alopecia areata had significantly lower serum vitamin D levels and a higher prevalence of vitamin D deficiency compared to people without the condition.

Alopecia areata patients often have low vitamin D levels.

This study found that patients with alopecia areata had significantly lower serum vitamin D levels and higher odds of vitamin D deficiency, but no significant difference in serum calcium levels, compared to controls.

This study analyzed 19 articles and found that vitamin D significantly improved the hormonal profile in women with PCOS, with greater effects observed after 8-week interventions compared to 12-week ones.

In this study, topical and intralesional vitamin D3 and its analogs were found to be effective and safe treatments for mild-to-moderate alopecia areata, achieving a 53.75% success rate, though intralesional vitamin D3 was less effective than other treatments like corticosteroids.

This study found that patients with alopecia, particularly alopecia areata and female pattern hair loss, often have vitamin D deficiency, suggesting that screening for vitamin D could benefit these patients.

This case report highlights a rare incidence of systemic lupus erythematosus in a patient with sickle cell trait, emphasizing the need for awareness of autoimmune disease associations beyond sickle cell disease.

This review discusses the association between vitamin D receptor polymorphisms and polycystic ovary syndrome, noting the need for further research on their impact on the disorder's manifestations.

This case study reported significant improvement in autoimmune-related symptoms, including complete hair regrowth, in a patient with systemic lupus erythematosus and alopecia areata after treatment with the LGS Protocol.

This study found that vitamin D levels in children with autoimmune alopecia were often below optimal, but did not suggest a need for extra vitamin D screening beyond standard practices.

This study observed that 25-hydroxyvitamin D3 restored rickets symptoms in genetically modified rats, suggesting its direct action through vitamin D receptor pathways.

This review discusses the molecular role of the vitamin D receptor in regulating various biological actions such as bone mineralization and reports no new clinical results, highlighting the complexity of vitamin D's function in multiple tissues.

This review discusses the role of vitamin D receptor signaling in hair follicle biology for alopecia treatment and underscores the need for continued research, without presenting new clinical results.

In this study, only Vdr-knockout rats showed both abnormal skin formation and alopecia, which may provide insights into vitamin D receptor function and its role in the hair growth cycle.

This review discusses the multifaceted role of vitamin D in the body, noting its influence on calcium balance, hair cycle maintenance, cell proliferation, cardiovascular function, and immune modulation, with no new clinical results reported.

This study observed that patients with alopecia areata had significantly lower serum 25-hydroxyvitamin D levels than healthy controls, with a trend toward even lower levels in more severe cases.

This review discusses the potential role of vitamin D deficiency in cardiovascular and renal diseases and suggests that supplemental vitamin D could benefit cardiovascular outcomes, especially in African American and postmenopausal women; it reports no new clinical findings.

This study found that CRP levels were elevated in alopecia areata patients, with an inverse linear association between serum vitamin D and CRP levels specifically noted in ophiasis AA.

This study found that patients with non-scarring alopecia, such as androgenetic alopecia and female pattern hair loss, have lower serum levels of 25-hydroxyvitamin D and a higher incidence of vitamin D deficiency compared to healthy controls.

Adequate vitamin D is crucial for skin health and should be considered in dermatology.

Vitamin D is crucial for skin health and managing skin diseases.

This study found that patients with alopecia areata had significant systemic inflammation and vitamin D deficiency, with both conditions more pronounced as disease severity increased.

This review discusses the relationship between vitamin D and various skin diseases but reports no new clinical results, emphasizing the need to assess and correct vitamin D deficiencies.

This review discusses the relationship between vitamin D and various skin diseases, highlighting the importance of evaluating vitamin D status and addressing deficiencies, and reports no new clinical results.

This study found that formulating raloxifene in nano-lipid carriers significantly enhanced its permeation and cytotoxicity against cancer cells compared to raw raloxifene.

This review discusses the potential risk mechanisms for COVID-19 in women with polycystic ovarian syndrome due to hyperandrogenism and calls for further research, but reports no new findings.