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Vertebrate skin evolved to be more specialized and complex, especially in land animals.

This study concluded that combining vertical and transverse sections of scalp biopsy specimens improves diagnostic yield for certain hair disorders without increasing costs.

This study found that significant hair loss in about one-third of patients after vertical gastroplasty was reversed by zinc supplementation.

This study found that vertical sections of alopecia biopsy specimens had a higher concordance rate with the original combined diagnosis compared to transverse sections alone, although both methods have their pros and cons.

Transamidases are present in the epidermis but their exact role is unclear.

This article provides departmental contact information for Dr. Dirk M. Elston at the Geisinger Medical Center and reports no research findings.

This study found that older men with vertex balding had lower levels of IGFBP-3 and higher levels of IGF-1 in their plasma.

This study found that 5% minoxidil topical foam was effective in stabilizing hair density and scalp coverage in men with moderate androgenetic alopecia over 104 weeks, with good safety and tolerability.

This study suggests that for single biopsy specimens, transverse sections may be preferable for diagnosing noncicatricial alopecia, while vertical sections may be better for suspected lichen planopilaris.

This study reports that horizontal sections of scalp biopsies improve the diagnosis of alopecia areata, especially when characteristic inflammatory infiltrates are missing.

This study found that SDR5A1 gene expression was similar between hirsute women, normal women, and men, suggesting it may not explain differences in hair growth among these groups.

This study found that vertical sleeve gastrectomy improved metabolic, behavioral, and reproductive symptoms in a rat model of PCOS, suggesting it may be a potential therapy for specific aspects of PCOS.

This study explored dermatoscopic and histopathologic findings of central centrifugal cicatricial alopecia beyond the vertex scalp, suggesting that dermatoscopy might serve as a less invasive diagnostic tool for subclinical disease.

In this study, transverse sectioning of scalp biopsy samples showed higher diagnostic accuracy than vertical sectioning for noncicatricial alopecia, although both techniques are important for accurate diagnosis.

This study found that older men with vertex balding have lower circulating levels of the protein IGFBP-3 and higher levels of IGF-1.

This article discusses ideal techniques for harvesting donor tissue in hair restoration surgery but reports no new clinical results.

This study found that men with vertex baldness had higher serum dihydrotestosterone levels compared to those with frontal baldness, suggesting different hormonal profiles between these two groups in androgenetic alopecia.

This letter to the editor discusses the prevalence of frontal-vertex baldness and its association with family history in Korean men but reports no new findings.

This study reported that two male patients with diffuse unpatterned alopecia exhibited donor-area involvement in both the vertex and occiput, challenging the assumption of occipital stability for hair transplantation, and showed partial improvement following treatment with oral finasteride and topical minoxidil.

This paper introduces the Vertex Overload Framework for androgenetic alopecia, suggesting that chronic mechanical and thermal stress on the vertex contributes to hair follicle miniaturization, with androgens acting as co-mediators of stress adaptation rather than isolated causes.

This study offers a new perspective on androgenetic alopecia, suggesting that hair loss at the vertex and frontal scalp results from mechanical and thermodynamic stress, alongside androgen activity, and proposes that reducing mechanical tension and improving local microcirculation could complement traditional treatments.

In this study, two male patients with androgenetic alopecia who had previously undergone hair transplants showed increased hair regrowth after receiving verteporfin injections, with a 63% mean increase in dense donor sites, 38% in thinning areas, but no growth in bald areas.

In this Stanford study, verteporfin was used to promote scarless skin regeneration by inhibiting YAP activity in a 27-year-old female, resulting in increased hair density at the treated site compared to the untreated control.

In this study, hypoxic conditions were found to enhance stemness in hair follicle neural crest stem cells, while inhibiting the Hippo pathway significantly decreased their proliferation.

Results are not reported for this study, which used a directed acyclic graph to analyze the association between chest hair amount and prostate cancer, adjusting for age and ancestry.

This case report describes a 39-year-old female with cutis verticis gyrata and cicatricial alopecia, emphasizing the need for further understanding of the potential genetic associations and underlying mechanisms.

Trichoscopy is effective in diagnosing trichotillomania by showing specific hair patterns.

This study compared the clinical effectiveness of platelet-rich plasma therapy with minoxidil for treating hair loss in men, suggesting PRP is a promising option.

This study conducted in a hair restoration clinic found that using the vertical scalp mobility method resulted in a significantly greater number of hairs available from the donor strip compared to the horizontal method, with an increase of approximately 970 hairs (P < .05).

This study found that polyamine levels were higher in the vertex hair than in occipital hair among patients with pattern baldness, suggesting a relation to hair loss development in the scalp's vertex region.