Metabolic, Behavioral, and Reproductive Effects of Vertical Sleeve Gastrectomy in an Obese Rat Model of Polycystic Ovary Syndrome

    January 2014 in “ Obesity surgery
    Ilana B. Ressler, Bernadette E. Grayson, Randy J. Seeley
    TLDR Vertical sleeve gastrectomy improved metabolism, behavior, and reproduction in obese rats with PCOS.
    The study demonstrated that Vertical Sleeve Gastrectomy (VSG) significantly improved metabolic, behavioral, and reproductive parameters in an obese rat model of Polycystic Ovary Syndrome (PCOS). VSG led to reduced body weight, improved glucose tolerance, decreased anxiety-like behavior, increased estrous cycling, and reduced ovarian cysts. These findings suggested that VSG could be a beneficial intervention for managing PCOS symptoms in obese individuals.
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