Supplementary Figure 2 From Male-Pattern Vertex Baldness Trajectories, Chest Hair Patterns, and Odds of Overall and Aggressive Prostate Cancer

A large case-control study in Montreal, Canada, involving 1,931 prostate cancer cases and 1,994 controls, examined the relationship between hair patterns and prostate cancer risk. The study found that early-onset vertex baldness at age 30 is associated with increased odds of overall prostate cancer, with an odds ratio (OR) of 1.30. Men with early moderate vertex baldness progressing to severe baldness had higher odds of both overall (OR, 1.42) and aggressive prostate cancer (OR, 1.98). Additionally, men with little chest hair had higher odds of aggressive tumors compared to those with more chest hair. These findings suggest that early-onset vertex baldness and chest hair amount could serve as biomarkers for aggressive prostate cancer, and incorporating these factors into risk prediction models should be considered.