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This integrative literature review revealed that chronic stress, characterized by elevated cortisol levels, negatively impacts hair follicle integrity and contributes to alopecia by promoting the premature transition from the growth phase to the resting phase of the hair cycle.

This study found that bioconjugating 16-methylheptadecanoic acid (16-MHA) to damaged hair can mimic the protective properties of 18-methyleicosanoic acid (18-MEA), restoring the hair's structural integrity and moisture homeostasis, even after washing.

This study found that disrupted cholesterol homeostasis impairs hair regrowth in individuals with primary cicatricial alopecia by damaging hair follicle stem cells, highlighting the importance of cholesterol in maintaining stem cell function and hair follicle integrity.

This study developed finite element models to examine skin's biomechanical properties, finding that structural heterogeneities like Rete ridges and hair follicles create distinct stress and strain patterns that may influence mechanosensation and skin integrity.

This review discusses the diverse roles and characteristics of epidermal and dermal stem cells in skin regeneration and aging, highlighting their potential applications in regenerative medicine and reports no new clinical results.

In this study, researchers observed that organic traffic to Spanish contract cheating websites rose during the COVID-19 pandemic but decreased from 2023, possibly due to the increasing use of generative AI tools.

This review discusses how dysfunction in keratinocyte adhesion affects skin integrity and conditions like alopecia and keratoderma, highlighting the roles of intercellular junctions, and reports no new clinical results.

This study assessed the effects of chemical treatments on hair fiber integrity and found that conditioners with vegetable oils like jojoba and coconut enhanced hydrophobicity and reduced combing friction except for jojoba, while participants preferred these oil-containing conditioners over the base formulation.

This study found that using a microfiber towel to dry human hair better preserves hair keratin integrity and wear resistance compared to blow-drying or using a cotton towel, as indicated by stronger alpha-helix structure in FTIR analysis.

This article reviews the genetic foundations of keratins in maintaining epithelial tissue integrity and links specific keratin variants to diverse ichthyosis forms, without presenting new clinical findings.

This review discusses the roles and interactions of intestinal intraepithelial lymphocytes in maintaining mucosal barrier integrity and highlights how their dysregulated responses may contribute to intestinal pathologies.

This review discusses the role of keratins in maintaining epidermal structure and function and reports no new results; the authors emphasize the lack of rational therapies for skin disorders linked to keratin mutations.

This review highlights that collagen XVIIα1's role in maintaining dermal-epidermal junction integrity and hair follicle stem cell maintenance is compromised with age due to reduced levels and increased processing, potentially affecting skin and hair aging.

This study demonstrates that keratin K2 is crucial for proper keratinocyte structure and function in specific mouse skin areas, and its deficiency leads to cellular aggregates and skin abnormalities.

This study found that CTHRC1 is crucial for sweat gland function and vascular network integrity in mice, and its administration improved sweat gland performance by reconstructing nearby blood vessels.

This study demonstrated that engineered exosomes carrying EGF and FGF restored hair density and follicle integrity in an androgenetic alopecia mouse model by reactivating hair follicle growth factors, offering a novel therapeutic approach without immunogenic reactions or systemic toxicity.

This editorial from Advances in Clinical and Experimental Medicine analyzed and discussed selected author instruction guidelines, emphasizing the importance of fulfilling certain requirements before peer review, such as financial disclosures and quality of tables and figures, for maintaining ethical integrity and efficient publication processes.

This study found that combining Bioscalp with Ultra Exo Booster and Ultra S Line Plus significantly promoted hair growth and maintained hair bulb integrity in cultured hair follicles from Korean adults.

Quickly fix tissue in formalin after excision to preserve it.

This study found that IL-17A-producing γδ T cells play a key role in bone fracture healing by promoting bone formation, with deficiencies leading to impaired repair in mice.

This study found that RSPO1 mutations in patients with a 46XX disorder of sexual development contribute to impaired skin integrity and increased risk of squamous cell carcinoma in areas subject to friction.

This review discusses how the nuclear lamina integrates biochemical and mechanical signals to influence gene expression and skin homeostasis, but reports no new clinical results.

This study suggests that the keratins found in reptile and bird skin appendages evolved independently from mammalian hair keratins, highlighting convergent evolution in these species.

This study validated the HS 3D-SeboSkin model as a reliable tool for preclinical research, effectively preserving the structure and biomarker expression of lesional and perilesional HS skin ex vivo.

This study found that topical application of recombinant human MG53 protein mitigated nitrogen mustard-induced skin injuries in mice by preserving epidermal integrity and hair follicle structure.

This study discusses how redox imbalance, specifically through reduced Insulin-like Growth Factor-1 mediated by the transcription factor JunB and sphingolipid metabolism changes, contributes to skin aging by depleting stem cell pools and altering the extracellular matrix, ultimately impacting skin integrity and function.

This review discusses current airway regeneration research efforts and reports no new experimental results, highlighting the need for clinical interventions to enhance airway repair.

This study found that VE-cadherin and Alk1, traditionally linked to vascular functions, also play crucial roles in maintaining nerve homeostasis in mice during hair growth cycles by modulating certain cell populations.

In this review, researchers detail how immunosenescence and chronic neuroinflammation contribute to Parkinson's disease progression, exploring potential therapeutic strategies targeting this axis, such as senolytic agents and immune rejuvenation, while highlighting associated challenges and future research needs.

This review summarizes the cell type distribution and functional significance of human keratins, emphasizing their roles in tumor diagnosis and potential clinical applications, and reports no new clinical findings.