research Antagonistic Effect of Potassium Iodide in Baldness due to Thallium Acetate
Potassium iodide prevents hair loss and reduces toxicity from thallium acetate.
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research A multi-omic single-cell landscape of perinatal mouse skin maps lineage specification and reveals shared dynamics in human fetal skin
This study used integrated single-cell chromatin and transcriptomic analyses in developing mouse skin to uncover gene networks involved in skin lineage specification and identified Mef2c+ upper fibroblasts as potential precursors to certain muscle-like structures, with cross-species findings in human skin.
research Ferulic acid promotes hair growth via estrogen receptor alpha activation in cultured human dermal papilla cells
This study found that Cnidium officinale extract and its compound ferulic acid improved hair growth by promoting dermal papilla cell function and mitochondrial activity, suggesting their potential as a new treatment option for alopecia, possibly through estrogen receptor alpha activation.
research NAD⁺ Biology in Ageing and Chronic Disease: Mechanisms and Evidence across Skin, Fertility, Osteoarthritis, Hearing and Vision Loss, Gut Health, Cardiovascular–Hepatic Metabolism, Neurological Disorders, and Muscle
This narrative review summarizes evidence on NAD⁺ biosynthesis and turnover, highlighting that while NAD⁺ precursors like NR and NMN consistently boost NAD⁺ levels in preclinical and human studies, clinical outcome results remain varied, indicating a need for more standardized human trials.
research Optimizing clinical monitoring and management guidelines for capivasertib in HR-positive/HER2-negative advanced breast cancer: expert opinion
In the phase 3 CAPItello-291 trial, capivasertib combined with fulvestrant significantly increased progression-free survival in patients with advanced breast cancer with specific genetic alterations, but the authors highlight that managing side effects like diarrhea, rash, and hyperglycemia is crucial for optimizing treatment adherence and outcomes.
research Efficacy and Safety of Spironolactone in Acne Management
This paper reviews the current evidence regarding the off-label use of spironolactone for acne management, noting that despite its long-standing application in acne treatment, it has not yet received FDA approval for this indication.
research If Women Just had Their Hormones Back the Way they Were!
This article examines when it is appropriate to prescribe estrogen for women with hormonal imbalances, utilizing decades of clinical practice, expert consultation, and a comprehensive literature review.
research Twist2 contributes to skin regeneration and hair follicle formation in mouse fetuses
This study explored the role of Twist2 in fetal wound healing in embryonic mice, observing that its expression was vital for scarless regeneration and normal hair follicle formation; Twist2 knockdown led to visible scars and defective follicle formation.
research Hair fall and its homoeopathic management
This abstract discusses the importance of physicians understanding hair disorders and their assessment, noting that homeopathic remedies have shown success in treating hair issues, allowing for tailored patient solutions within holistic medicine.
research If women just had their hormones back the way they were! (for youthful feeling-balance your hormones!)
This article provides evidence on when it is appropriate to prescribe hormone therapy for women by reviewing cases from the author's practice and international literature, emphasizing the importance of primary care in managing hormonal imbalances.
research Do transgender patients experience more barriers in accessing oral healthcare and suffer an increased risk of poor oral health: can this lead to a lower oral health-related quality of life?
This study identified that transgender patients face barriers in accessing oral healthcare, including discrimination and harassment, leading to increased stress, poorer oral health, and a diminished quality of life related to oral health.
research Lrig1-expressing epidermal progenitors require SCD1 to maintain the dermal papilla niche
This study presents evidence that hair matrix progenitors and the enzyme Stearoyl CoA Desaturase 1 may play a role in maintaining the dermal papilla niche via autocrine Wnt and paracrine Hedgehog signaling in mice.
research An Overview of Harmful Effects of Polycystic Ovary Syndrome
This article discusses the treatment options for women with polycystic ovarian syndrome and notes the need for further research to improve patient management.
research How the dental profession can reduce the risk profile in facial aesthetics
Dental professionals should ensure safety in facial aesthetics by being properly trained and registered.
research Development of cosmeceutical cream for dermatitis and acne vulgaris
This source describes the development of a new cream combining salicylic acid and retinol, assessed for its potential to alleviate itching in dermatitis and treat acne vulgaris, with stability and patch testing indicating no irritation or allergic reactions.
research Psoriasis and Hepatitis C: Improvement with Interferon
During treatment with interferon/ribavirin for hepatitis C, this study observed significant and lasting improvement in a patient's psoriasis without additional psoriasis-specific therapies.
research To be hairless or wise?
In this study, researchers discovered that the interaction between the hairless protein and the wise protein is crucial for hair-follicle regeneration, helping bald mice regrow fur.
research The variable cell
This study suggests that the interaction between the hairless and wise proteins can help bald mice regrow fur, highlighting its essential role in hair-follicle regeneration.
research Trichoblastic Carcinoma (“Malignant Trichoblastoma”) with Lymphatic and Hematogenous Metastases
Long-standing benign tumors can become cancerous, especially in people with weakened immune systems.
research A Fatty Acid / Protein Complex in Human Hair
A fatty acid/protein complex in human hair helps protect it from damage.
research Modeling Oxidative Stress-Linked Telogen Effluvium Using Monte Carlo Simulation of Published Trichoscopy Norms and Cannabis Exposure Distributions
In this study, a Monte Carlo-generated synthetic cohort analysis found that higher simulated cannabis exposure was linked to increased self-assessed hair loss severity and reduced follicular density, suggesting potential connections worth exploring in further clinical research.
research Low temperature abolishes human cellular circadian rhythm through Hopf bifurcation
This study found that cold exposure disrupts the circadian rhythm in cultured human cells by reducing oscillation amplitude, which is restored upon rewarming, while human hair follicle cells showed minimal amplitude sensitivity to temperature changes, suggesting an evolutionary advantage related to Hopf bifurcation dynamics.
research Approach to Dermatological Care of Muslim Women
This study reviews the barriers faced by Muslim women in accessing dermatological healthcare, emphasizing the need for cultural competency regarding their values and practices to improve care within this understudied area.
research Retrospective diagnosis of intrauterine diselementosis in newborn calves
This study concluded that the elemental composition of tail brush hair in newborn calves can indicate trace element supply to the fetus during the last months of pregnancy.
research It's Not “Like Growing Grass”
Blocking a compound called prostaglandin D₂ might help treat hair loss.
research Hair Growth promoting activity of Pig oil on Wister rats
In this study, pig oil was found to significantly promote hair growth in Wister rats, performing better than the standard Minoxidil treatment from the 15th day onward.
research Investigation of the role of biotin in the regulation of wool growth in sheep hair follicle cultured in vitro
In this study, biotin supplementation was found to significantly increase wool follicle viability and metabolic activity in vitro, with the highest effects observed at 0.5 mg L⁻¹ concentration.
research Polymeric nanoparticles‐based topical delivery systems for the treatment of dermatological diseases
This review discusses nanoparticle-based topical delivery systems for treating skin diseases and presents no new clinical findings; it emphasizes natural polymer-based nanoparticles and future applications like targeted drug delivery.
research Microtechnology-based methods for organoid models
This review discusses recent advances in microfabrication and microfluidic technologies for improving the production of organoids and spheroids, but it reports no new experimental results.
research Tissue Engineering and Regenerative Medicine: Achievements, Future, and Sustainability in Asia
This review provides an overview of recent tissue engineering and regenerative medicine developments in Asia, highlighting significant advances, representative research achievements, and discussing future directions, without presenting new research results.