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Gynecologists should provide comprehensive care for transgender patients, including mental health evaluation, hormone therapy, and surgical options, while monitoring for side effects and ensuring patient safety.

The guidelines recommend informed consent for gender-affirming treatments and stress the importance of personalized, culturally sensitive care for transgender individuals.

SHBG may be a useful early indicator and treatment target for PCOS.

Finasteride treatment changes urine metabolomics and steroid signatures, potentially monitoring effectiveness but may cause sexual side effects.

Nandrolone and oxandrolone could help treat male health issues like muscle loss and low testosterone.

Many males in Jordan misuse oral contraceptive pills for hair growth, muscle gain, and acne treatment.

Athletes use steroids to enhance performance despite health risks and legal issues, and education on their dangers is needed.

DNA profiling in forensics has improved, but predicting physical traits and ancestry from DNA has limitations and requires ethical consideration.

Many men misuse oral contraceptive pills for things like hair growth and muscle gain.

Noncoding dsRNA boosts hair growth by activating TLR3 and increasing retinoic acid.

Researchers found potential urine markers for polycystic ovary syndrome, including testosterone-glucuronide and 11α-hydroxyprogesterone, which may help diagnose the condition.

JAK inhibitors show promise for treating skin and hair disorders but need more research on long-term safety and effectiveness.

The research provides a gene-based framework for hair biology, highlighting the Hippo pathway's importance and suggesting links between hair disorders, cancer pathways, and the immune system.

The document recommends a team-based approach and personalized care for managing diabetes in teenagers.

Vav2 changes how hair follicle stem cells' genes work as they age, which might improve regeneration but also raise cancer risk.

Increased PPARGC1α relates to hair thinning in common baldness.

Autism's genetics are linked with early age of puberty and less hair loss, but not with hormone levels or polycystic ovary syndrome.

DNA methylation changes in women with PCOS could be used as disease markers and suggest new treatment targets.

Activating Notch signaling can kill basal cell carcinoma cells.

A weight loss program with a special fast helped patients lose an average of 41-47 pounds and improved their health, but maintaining the weight loss was challenging.

Melatonin helps Cashmere goats grow more hair by affecting certain genes and cell pathways.

The enzyme 5α-reductase type 1 is important for blood vessel development and fertility in the uterus.

Effective PCOS treatments require targeting specific signaling pathways.

The enzyme 5α-reductase is important for proper blood vessel development during the fertility-related transformation of the uterus lining.

Fibroblasts, cells usually linked to tissue repair, also help regenerate various organs and their ability decreases with age. Turning adult fibroblasts back to a younger state could be a new treatment approach.

miR-140-5p in certain cell vesicles helps hair growth by boosting cell proliferation.

Low ERCC3 gene activity is linked to non-pigmented hair growth.

Fat cells in the skin help start healing and form important repair cells after injury.

Lifestyle changes improve metabolism and fertility in overweight PCOS patients; anti-obesity drugs show potential but need more research.

The research found different metabolism changes in PCOS patients and suggested new potential markers for diagnosing PCOS with or without insulin resistance.