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Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.

Skin fat has important roles in hair growth, skin repair, immune defense, and aging, and could be targeted for skin and hair treatments.

Mutations in specific keratin genes cause improper hair structure in mice due to faulty keratin protein assembly.

The S250C variant in a gene may cause autoimmunity and immunodeficiency by impairing protein function.

Elaine Fuchs' research shows how skin stem cells maintain health, aid in healing, and are involved in cancer.

NF-κB is crucial for different stages and types of hair growth in mice.

A gene variant increases the risk of a type of hair loss by affecting hair protein production.

Patients with cutaneous lupus are most concerned about self-consciousness, physical symptoms, and disease progression.

Bolandiol, a synthetic steroid, builds muscle and bone without greatly affecting sex glands, and works differently from other hormones.

Researchers found potential new targets for treating melanoma and nonmelanoma skin cancers, and identified a possible cause and treatment for male pattern baldness and eczema.

Genetic marker rs12558842 strongly linked to male hair loss.

A new mutation in the XEDAR gene might cause a rare skin condition called hypohidrotic ectodermal dysplasia.

Targeting the HEDGEHOG-GLI1 pathway could help treat keloids.

Gene therapy in mice increased lifespan and improved health without causing cancer.

Sebocytes play a key role in controlling androgen levels in human skin.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.

Different types of fibroblasts play various roles in both healthy and diseased tissues, and understanding them better could improve treatments for fibrotic diseases.

The ITGB6 gene is important for tissue repair and hair growth, and mutations can lead to enamel defects and other health issues.

Certain gene variations are not a major cause of male infertility in Nigerian men.

Centipeda minima extract helps hair grow by activating important growth signals and could be a promising hair loss treatment.

Nutrients like vitamins, copper, zinc, and amino acids are crucial for healthy hair and wool growth.

The review highlights the importance of stem cells in hair health and suggests new treatment strategies for hair loss conditions.

Hair follicles in the back of the rosette fancy mouse have reversed orientations due to a gene mutation.

SOX2 is crucial for skin cell function and hair growth, and it plays a role in skin cancer and wound healing.

Disrupted cholesterol production impairs hair follicle stem cells, leading to hair loss.

The document emphasizes the importance of ongoing research and ethical considerations in genome editing and cellular reprogramming.

Hair loss patterns differ between males and females due to 5 master regulators and JAK-STAT signaling affects hair growth.

Keratins are crucial for cell structure, growth, and disease risk.

Stem cell self-renewal is complex and needs more research for full understanding.