January 2024 in “International Journal of Biological and Environmental Investigations” This study developed and validated a reliable RP-HPLC method for accurately quantifying dutasteride in pharmaceutical formulations and bulk pharmaceuticals using a Shiseido C18 analytical column, demonstrating precision, accuracy, and sensitivity across a concentration range of 10 to 22 ppm.
January 2005 in “Yaowu fenxi zazhi” This study established a mathematical model for measuring uncertainty in the HPLC determination of tablet content and content uniformity, which the authors concluded to be reasonable and reliable.
2 citations
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June 2020 in “BMC Health Services Research” This study found that after a health warning, off-label flutamide use by women reduced significantly in Spain, although misuse among ambulatory patients remains an issue.
12 citations
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January 2007 in “Acta dermato-venereologica” This review discusses the classification and regulation challenges of anti-ageing cosmetics in Europe and reports no new findings; it calls for increased transparency to help consumers make informed choices.
This study reports on a new semantic annotation approach used to identify substances in MEDLINE abstracts responsible for adverse drug reactions, with promising performance shown by a prototype system.
April 2020 in “The Journal of Urology” This study found that big chain pharmacies in Pennsylvania charged significantly higher prices for generic BPH medications compared to independent pharmacies, which had more regional price variation.
February 2025 in “Biointerface Research in Applied Chemistry” This study outlines the potential of drug repurposing to discover new uses for existing medications, emphasizing its cost-effectiveness, efficiency, and ability to address rare diseases by targeting novel biological mechanisms and relying on established safety profiles.
188 citations
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October 2012 in “The AAPS Journal” This review discusses strategies for developing semi-solid topical generic products to match the quality of reference-listed drugs, using concepts like quality by design and reverse-engineering, but reports no new results.
This investigation reports a new RP-HPLC method for accurately estimating Finasteride and Tamsulosin Hydrochloride in bulk and tablet forms, which may serve in routine pharmaceutical analysis.
2 citations
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May 2017 in “Kesmas: Jurnal Kesehatan Masyarakat Nasional” This study found that counterfeit disease-curing medicines are most prevalent in countries with low Human Development Index, while lifestyle drugs are found in both high and low HDI countries.
January 2013 in “Zhongguo yaofang” This study established a sensitive and reproducible method for determining the levels of four organic solvents in finasteride raw materials, meeting the requirements of the Chinese Pharmacopeia.
June 2014 in “Basic & Clinical Pharmacology & Toxicology” This study found that alkaloids isolated from Cucumis metuliferus fruit pulp demonstrated antiviral activity against IBDV in chicken embryo fibroblast cells and NDV in 10-day-old embryonated chicken eggs, while being non-cytotoxic.
29 citations
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October 2020 in “Environmental health perspectives” This study found that several preservatives, including triclocarban and triclosan, showed potential endocrine-disrupting effects on various nuclear receptors in both in silico and in vitro models.
2 citations
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November 2004 in “Hospital pharmacy” This article reviews adverse drug reactions, emphasizes methods of prevention, and encourages reporting to the FDA's medWatch program, but presents no new study findings.
October 2008 in “Clin-alert” This abstract lists keywords related to various medications and therapies, but it does not provide new study results or findings.
1 citations
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July 2020 in “Reviews in separation sciences” This study developed a simple method to determine finasteride, indapamide, and tiemonium methylsulfate in pharmaceuticals by using their ability to form silver nanoparticles measurable via spectrophotometry.
January 2014 in “China Surfactant Detergent & Cosmetics” This study established a method using reversed-phase high performance liquid chromatography to determine finasteride concentration in hair cosmetics, showing a strong linear relationship with mass concentration and recoveries between 90.3% and 102.0%.
January 2020 in “Asian Journal of Chemistry” This study demonstrated that FT-Raman spectroscopy is effective for identifying finasteride polymorphs in tablets and detecting the presence of alternative polymorphs down to about 15% concentration.
February 1999 in “Drugs in R & D” The document concludes that various drugs for men's health issues are in development, with treatments for sexual dysfunction and prostate conditions being the most advanced.
January 2003 in “Pharmaceutical Journal of Chinese People's Liberation Army” This study developed a simple and accurate HPLC method to determine the dissolution of finasteride tablets, achieving a high recovery rate and linear calibration for finasteride detection.
1 citations
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January 2012 in “Analytical chemistry, an Indian journal” This study successfully developed and validated a sensitive and precise liquid chromatography method for simultaneously estimating tamsulosine hydrochloride and finasteride in tablets, showing high accuracy and minimal interference from excipients.
14 citations
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July 2017 in “Monatshefte für Chemie - Chemical Monthly” This review discusses the analysis of pharmaceutical relics from prehistoric times to the twentieth century and emphasizes the need for a multifaceted approach, but it presents no new experimental results.
March 2026 in “The Aging Male” This retrospective pharmacovigilance study reviewed adverse event reports from 2004 to 2025 for drugs treating benign prostatic hyperplasia, identifying distinct safety signals for α1-blockers, 5ARIs, and PDE5I, including some potential new adverse events that require further investigation.
3 citations
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October 1994 in “Journal of Labelled Compounds and Radiopharmaceuticals” This synthesis report details the successful development of a C-14 labeled isotopomer of LY300502, a 5α-reductase inhibitor, through a multi-step radiochemical process.
1 citations
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November 2010 in “Value in Health” Pill splitting increased generic finasteride sales but didn't affect branded finasteride sales.
This study identified distinct and significant adverse event patterns across different drug classes used to treat benign prostatic hyperplasia, confirming known risks and suggesting novel safety signals for further investigation.
7 citations
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January 2001 in “PharmacoEconomics” This article discusses lifestyle drugs, their subjective value, and the challenges in determining who should pay for them, highlighting the need for consensus on priorities and strategies.
2 citations
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September 2018 in “Journal of Separation Science” This study demonstrated that using finasteride impurity as a non-isotopically labeled internal standard in paper spray ionization–mass spectrometry can effectively and efficiently measure finasteride tablet dissolution, achieving results comparable to high-performance liquid chromatography.
9 citations
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February 2018 in “Journal of Pharmaceutical and Biomedical Analysis” This study validated a highly selective and fast LC–MS/MS method for accurately measuring levels of tadalafil and finasteride in human plasma, adhering to international bioanalytical guidelines.
July 2007 in “Journal of Generic Medicines” The UK High Court revoked Lundbeck's patent for Escitalopram, and second medical use claims based on dosage were not considered novel.