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The document concludes that various drugs can manage symptoms and metabolic issues in women with PCOS.

Leptin-deficient mice, used as a model for Type 2 Diabetes, have delayed wound healing due to impaired contraction and other dysfunctional cellular responses.

No consistent link between genotype and phenotype in 5-α-Reductase type 2 deficiency.

Inhibitors of the enzyme 5 alpha-reductase could potentially treat disorders like prostate cancer and baldness.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

A cluster of sulfur-rich hair protein genes was found on chromosome 17.

Maintaining the right amount of retinoic acid is crucial for healthy hair and skin.

Men with Type 2 Diabetes have lower DHT levels, which may affect fertility and lipid profiles.

Perilla frutescens, an East Asian plant, contains 400 bioactive compounds that have various health benefits, including anti-inflammatory, antidepressant, and anticancer effects, and can treat conditions like diabetes, skin allergies, and neurological disorders.

Male pattern baldness is often genetic and linked to a hormone, with treatments like finasteride and minoxidil being effective for some men.

Phospholipase A2 enzymes play key roles in skin health and disease.

Recent findings suggest that genetic factors, immune system issues, and skin cell defects might contribute to the development of hidradenitis suppurativa.

PCOS is a complex condition that affects women's hormonal balance and metabolism, requiring lifestyle changes and medical management.

Polycystic Ovary Syndrome (PCOS) is a common condition in women that can cause metabolic, reproductive, and psychological issues, and requires lifestyle changes and medication for management.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Insulin resistance and high male hormone levels are major causes of Polycystic Ovary Syndrome.

Keratin 17 is modified by RSK1 in response to growth and stress, affecting skin growth and stress response.

The document concludes that Syndromes of Severe Insulin Resistance are rare disorders with limited treatment options.

PCOS has a strong genetic basis, but more research is needed to fully understand it.

Creatine monohydrate is safe and effective for muscle recovery and performance, especially for those with low creatine levels.

Most adrenal cortex tumors are benign and non-secreting, but proper diagnosis and treatment are important due to the rare possibility of cancer.

Trichohyalin is modified by enzymes to form strong structures in hair cells.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

TGase 3 helps build hair structure by forming strong bonds between proteins.

Honokiol might help reduce male skin aging by maintaining testosterone levels.

The enzyme 25 Hydroxyvitamin D 1 α-Hydroxylase is essential for healthy skin and recovery after skin damage.

Men with male-pattern baldness have more androgen receptors in their scalp's oil glands, which may contribute to hair loss.

The document suggests treating individuals with nonclassic congenital adrenal hyperplasia who show symptoms, especially those related to excess male hormones.

Human skin has multiple layers and functions, with key roles in protection, temperature control, and appearance.