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Terbinafine is more effective than itraconazole for toenail fungus, especially in older patients, and debridement improves its effectiveness.

Some skin diseases and their treatments can negatively affect male fertility.

MSCs and their exosomes may speed up skin wound healing but need more research for consistent use.

A new hydrogel made from human cells improves wound healing by working with immune cells to promote repair.

The KRTAP11-1 gene promoter is crucial for specific expression in sheep wool cortex.

Alopecia areata involves both innate and adaptive immunity, with specific genes linked to the disease.

Certain genes on chromosomes 6, 10, 16, and 18 may increase the risk of alopecia areata.

Bone marrow stem cells and their medium help hair regrowth.

Melatonin, usually known for sleep regulation, also has antioxidant properties that can protect skin, stimulate hair growth, and improve skin conditions, with topical application being more effective than oral use.

Genetically modified sheep with more β-catenin grew more wool without changing the wool's length or thickness.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Understanding skin structure and development helps diagnose and treat skin disorders.

Rosuvastatin improves lipid levels, reduces inflammation, but worsens insulin sensitivity in men with early-onset hair loss.

The research found that male pattern hair loss is mostly genetic and involves hair thinning due to hormonal effects and changes in gene expression.

Baldness in men with prostate cancer is linked to higher levels of certain sex hormones, but chest hair density is not.

The balance between androgen receptor and p53 is crucial for sebaceous gland differentiation.

The research provides a gene-based framework for hair biology, highlighting the Hippo pathway's importance and suggesting links between hair disorders, cancer pathways, and the immune system.

The document concludes that understanding genetic mutations in the PI3K-AKT-mTOR pathway can lead to better diagnosis and treatment for certain genetic skin disorders.

Hormone imbalances can cause specific skin changes, which may help in early detection of endocrine disorders.

Research on epidermal stem cells has advanced significantly, showing promise for improved clinical therapies.

HNG may help prevent the negative effects of chemotherapy on sperm production and white blood cell counts.

Rare changes in the KRT82 gene are linked to a higher risk of Alopecia Areata.

Androgens affect bone and fat cell development differently based on the cells' embryonic origin.

Immune cells in Hidradenitis suppurativa become more inflammatory and may be important for treatment targets.

Use "female pattern hair loss" term, assess androgen excess, treat with minoxidil and other medications if needed.

Hormone therapy affects hair growth in transgender individuals, with testosterone potentially causing hair loss in trans men and estrogen reducing facial/body hair in trans women; treatment options vary.

The document concludes that accurate diagnosis and treatment are crucial in dermatology, and it presents various findings on skin conditions and treatments.

The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.

Skin aging reflects overall body aging and can indicate internal health conditions.

SCD1 is important for hair growth by keeping the connection in skin cells where hair stem cells live stable.