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Researchers found new potential but less potent rat enzyme inhibitors using a 3D model.

Higher enzyme levels found in women with hair loss, suggesting hormone imbalance.

The developed model can predict effective 5-alpha-reductase enzyme inhibitors.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

The medications 5α-reductase inhibitors and spironolactone are generally safe for breast cancer patients on endocrine therapies and do not significantly increase breast cancer risk.

Special nanoparticles increased skin absorption of hair loss treatments with fewer side effects.

Hair loss drugs may cause sexual issues and infertility in men.

Finasteride improves hair growth in men with androgenetic alopecia.

Finasteride and dutasteride effectively treat hair loss, but may cause side effects like sexual dysfunction and depression.

New hybrid compound found to effectively prevent hair loss.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Both drugs lower DHT levels, with GI198745 being more effective.

Dutasteride protects dopamine neurons in Parkinson's mice, but Finasteride doesn't.

Finasteride and dutasteride reduce unwanted movements from Parkinson's disease treatment by normalizing certain brain signals.

Hair characteristics might be early signs of Type 2 Diabetes and could help with early prevention.

Researchers found four key proteins that affect the development of a specific hair type in Yangtze River Delta white goats.

5-alpha reductase inhibitors might worsen lung recovery in COVID-19 patients, suggesting a pause in their use.

Two types of 5α-reductase are in dog skin, which might make dutasteride better than finasteride for treating dog hair loss.

High testosterone to epitestosterone ratio in hair could predict male-pattern baldness.

The review suggests younger men taking 1 mg finasteride report more side effects, including sexual, skin, metabolic, and psychological issues.

Certain Chinese herbs, especially Cacumen platycladi, can promote hair regrowth and reduce hair loss-related hormone levels in mice.

5α-reductase inhibitors can cause serious and possibly lasting sexual and psychological side effects.

High-dose dutasteride reduces PMDD symptoms by stabilizing neurosteroid levels.

Rice bran extract can potentially treat hair loss by promoting hair growth and increasing the number of hair follicles.

The document concludes that recognizing specific histological features of different nonscarring alopecias is crucial for accurate diagnosis and understanding hair loss progression.

Proscar (finasteride) blocks 5α-reductase in sea urchin ovaries and testes, suggesting potential treatment for androgen-related conditions.

Glioblastoma cells can make androgens, which might help the tumor grow.

Dutasteride may help shrink prostate cancer tumors.

The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.

A type of collagen helps hair grow by boosting cell growth and activating a specific hair growth pathway.