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Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

The gene SDR5A1 is found in scalp hair of both hirsute and normal individuals, but it does not explain differences in hair growth.

No consistent link between genotype and phenotype in 5-α-Reductase type 2 deficiency.

Gene variant linked to prostate cancer, hormone levels, and hair loss.

The enzyme 5α-reductase is important for proper blood vessel development during the fertility-related transformation of the uterus lining.

The human type II 5α-reductase gene, linked to certain male health conditions, has a specific structure and low similarity to other related genes.

The human type II 5α-reductase gene has a specific structure important for understanding certain medical conditions.

A new compound effectively inhibits human 5α-reductase 1.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Changing the C-ring structure in certain compounds can make them better at blocking a specific human enzyme.

Bee venom helps hair grow and may work better than some common treatments.

Sebocytes play a key role in controlling androgen levels in human skin.

Many treatments for hair loss lack proper testing and FDA approval, so their effectiveness is uncertain.

The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Herbal extracts may help hair grow and could be an alternative to synthetic hair loss treatments.

Dicentrine reduced heart disease risk factors in rats, T-588 protected mice brains without side effects, Provir blocked herpes virus and lessened mouse symptoms, and LY191704 could treat hair loss and prostate issues.

Male yak hair growth is influenced by DHT synthesis, which is promoted by 5α-red1 and AR during growth phases, while E2 may inhibit growth through ERα.

Finasteride affects the male rat brain by reducing certain protein activation, but these effects may reverse after stopping the drug.

Acankoreoside J from Acanthopanax koreanum may help promote hair growth.

Understanding how androgens work is key for creating new treatments for prostate issues and hair/skin conditions.

Understanding how DHT works is important for diagnosing and treating hormone-related disorders.

The herbal mixture could potentially improve hair loss.

Dutasteride, usually used for prostate issues and hair loss, could potentially treat Amyotrophic Lateral Sclerosis (ALS) due to its neuroprotective, antioxidant, and anti-inflammatory properties, but more testing is needed.

Rice bran extract might help prevent hair loss.

Finasteride doesn't affect antipyrine metabolism, so interactions with cytochrome P-450 enzyme drugs are unlikely.

Exercise improves insulin sensitivity and hormone regulation in PCOS rats.

Hirsute women have lower type 2 17β-HSD enzyme levels, which improve with treatment.

Men with Type 2 Diabetes have lower DHT levels, which may affect fertility and lipid profiles.

Certain mutations in the H6PD gene cause Cortisone Reductase Deficiency by affecting hormone production.