March 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that type 2 immunity, especially involving ILC2 cells, helps maintain skin homeostasis by regulating the proliferation and community stability of hair follicle epithelial cells in the presence of Demodex mites.
46 citations
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October 1999 in “Journal of The American Academy of Dermatology” This study found that finasteride at 1 mg/day was the most effective dose for treating male pattern hair loss, with similar efficacy to 5 mg/day and better results than lower doses.
14 citations
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August 2022 in “Lupus Science & Medicine” This study found two patterns of Type 2 SLE symptoms: Intermittent symptoms resolving with Type 1 symptom remission and Persistent symptoms continuing regardless of Type 1 symptom activity.
July 2022 in “International Journal of Health Sciences (IJHS) (En línea)” In this study, researchers found that serum dihydrotestosterone levels were significantly lower in individuals with Type 2 Diabetes compared to healthy controls, with 90% of diabetics displaying subnormal levels.
22 citations
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October 2001 in “Biochemical Pharmacology” This study found that GI198745 acts as a time-dependent inhibitor of rat 5α-reductase type 2 but a rapid-equilibrium inhibitor of type 1, potentially making it more effective than finasteride in preventing rat prostate growth.
9 citations
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January 2007 in “Gynecological Endocrinology” This case report presents the first known instance of combined polycystic ovary syndrome and autoimmune polyglandular syndrome type 2 in a patient, exploring potential mechanisms for their interrelation.
January 2024 in “Srpski arhiv za celokupno lekarstvo” In this study, patients with diabetic retinopathy and peripheral occlusive arterial disease had significantly longer diabetes duration, higher HbA1c levels, poorer glycemic control, and were more often smokers compared to those without arterial disease, suggesting these factors contribute to disease development.
October 2025 in “Journal of the Endocrine Society” In this case report, a 21-year-old female with familial partial lipodystrophy type 2 and hyperandrogenism was found to have a rare Sertoli cell tumor of the ovary, highlighting an unusual presentation where links between these two rare conditions are still unknown.
June 2026 in “International Journal of Medical Science and Dental Health” In this study, researchers found that women with Type 2 Diabetes Mellitus and hair loss had significantly lower levels of ferritin, zinc, and vitamin D compared to men, and constructed a validated risk score to predict severe nutrient deficiencies in these patients.
1 citations
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October 2022 in “International Journal of Environmental Research and Public Health” This study found that Type 2 Diabetes was associated with a higher likelihood of Demodex folliculorum infestation in patients at a hospital in Peru.
42 citations
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June 1998 in “The journal of investigative dermatology/Journal of investigative dermatology” This study observed that PAI-2 is consistently expressed in differentiating cells of murine hair and nail, suggesting it may function as a marker of differentiation and possibly protect against premature cell death.
January 2023 in “International Journal of Contemporary Pediatrics” This case study describes a 5-year-old boy with vitamin D dependent rickets type 2, motor delays, and alopecia totalis who showed improved biochemical parameters with calcium and calcitriol treatment.
175 citations
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September 1998 in “British Journal of Dermatology” This study found that mutations in the K17 gene underlie both pachyonychia congenita type 2 and steatocystoma multiplex phenotypes, regardless of the specific mutation involved.
3 citations
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August 2015 in “Diabetes and Metabolic Syndrome: Clinical Research and Reviews” This study suggests that type 2 diabetes mellitus and polycystic ovary syndrome are separate medical entities despite both being linked to insulin resistance.
1 citations
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July 2024 in “Human Reproduction” This study found that for obese patients undergoing sleeve gastrectomy, concurrent type 2 diabetes is linked to worsened metabolic but milder reproductive aspects of PCOS and does not hinder the return to regular menstruation one year after surgery.
22 citations
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June 2010 in “Experimental Dermatology” This study reported that patients with alopecia areata have reduced expression of the melanocortin receptor MC2R in their scalp tissues compared to normal scalp, indicating potential involvement in the condition's pathophysiology.
June 2023 in “Journal of personalized medicine” This study found that dihydrotestosterone treatment may be more beneficial for height in children with 5-α-reductase type 2 deficiency compared to testosterone enanthate, especially in the prepubertal period.
8 citations
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April 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” This study identified biallelic variants in the LSS gene as a possible genetic cause of palmoplantar keratoderma-congenital alopecia syndrome type 2, highlighting the role of cholesterol synthesis in skin cornification.
October 2022 in “Endocrine journal” In this study of male patients with 46,XY 5α-reductase type 2 deficiency, DHT therapy was effective in achieving penile enlargement during infancy, while testosterone replacement therapy proved more beneficial during puberty, possibly due to increased conversion to DHT.
1 citations
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October 2021 in “Prilozi - Makedonska akademija na naukite i umetnostite. Oddelenie za medicinski nauki” This study found that among women with PCOS, 23% exhibited impaired glucose tolerance and 9% had type 2 diabetes, with age, BMI, and SHBG being key predictors of these glucose abnormalities.
January 2025 in “Global Health” This study found that Bangladeshi patients with type 2 diabetes mellitus had significantly lower serum vitamin E levels compared to healthy individuals, with lower levels particularly observed in female and older patients, emphasizing the potential importance of antioxidant status in managing the disease.
2 citations
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December 2013 in “BIRDEM Medical Journal” This study found that among type 2 diabetes patients, chronological age was significantly associated with the occurrence of periodontal diseases, which could influence metabolic control of diabetes.
February 2026 in “Cureus” In this narrative review, the authors compared monotherapy and combination therapy for type 2 diabetes, finding that while monotherapy is effective in early stages, combination therapy offers superior glycemic control and cardiovascular benefits, though it requires individualized selection for safety and adherence.
March 2022 in “Evidence-based Complementary and Alternative Medicine” This study found that critically ill pulmonary patients with deficiency syndrome were at a higher risk of developing type 2 myocardial infarction than those with phlegm syndrome.
2 citations
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January 2025 in “Cutis” This review examined the dermatologic side effects and potential treatments benefits of metformin and GLP-1/GIP agonists in managing skin conditions related to hormonal and immune effects in individuals with type 2 diabetes who are overweight or obese.
2 citations
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April 2023 in “Diabetes Metabolic Syndrome and Obesity” 2h-ICPR can help screen for insulin antibodies in type 2 diabetes patients.
July 2025 in “International Journal of Dermatology” 5 citations
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June 2008 in “British Journal of Dermatology” 1 citations
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January 2024 in “Sultan Qaboos University medical journal” In this study, mild adverse reactions to COVID-19 vaccines were reported among vaccinated staff and students, with females experiencing more reactions than males.
4 citations
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May 2019 in “Zeitschrift für Naturforschung C” This study found that Ishige sinicola extract stimulated osteoblast differentiation and bone formation in MC3T3-E1 cells, suggesting potential use for osteoporosis prevention and treatment.