research Repairing the Lungs One Breath at a Time: How Dedicated or Facultative Are You?
Lung repair involves both dedicated and flexible stem cells, important for developing new treatments.
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research Is COVID-19 a Risk Factor for Progression of Benign Prostatic Hyperplasia and Exacerbation of Its Related Symptoms?: A Systematic Review
COVID-19 might worsen symptoms and progression of benign prostatic hyperplasia, possibly due to inflammation and metabolic disturbances in the prostate gland. More research is needed to confirm this.
research The Probable Destructive Mechanisms Behind COVID-19 on Male Reproductive System and Fertility
COVID-19 may harm male fertility and damage the reproductive system.
research Cardiac and Renal SARS-CoV-2 Viral Entry Protein Regulation by Androgens and Diet: Implications for Polycystic Ovary Syndrome and COVID-19
Androgens and a high-fat diet may increase the risk of severe COVID-19 in women with PCOS by upregulating certain proteins in the heart and kidneys.
research Minoxidil Regulates Aging-Like Phenotypes in Rat Cortical Astrocytes In Vitro
Minoxidil may help reduce aging effects in brain cells.
research Inhibition of Rat Alpha-Reductases by Finasteride: Evidence for Isozyme Differences in the Mechanism of Inhibition
Finasteride effectively blocks rat enzymes, but with varying methods and strength.
research Improving Translational Research in Sex-Specific Effects of Comorbidities and Risk Factors in Ischemic Heart Disease and Cardioprotection: Position Paper and Recommendations of the ESC Working Group on Cellular Biology of the Heart
The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.
research Repurposing Existing Drugs for COVID-19: An Endocrinology Perspective
Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.
research Sleep Problems Are Associated with Development and Progression of Lower Urinary Tract Symptoms: Results from REDUCE
Poor sleep is linked to a higher risk of developing and worsening urinary problems in men.
research 3,3-Diphenylpentane Skeleton as a Steroid Skeleton Substitute: Novel Inhibitors of Human 5α-Reductase 1
A new compound effectively inhibits human 5α-reductase 1.
research Topical Minoxidil Treatment for Congenital Alopecia in Hypohidrotic Ectodermal Dysplasia
Minoxidil cream can safely treat hair loss in kids with ectodermal dysplasia.
research Dermal EZH2 Orchestrates Dermal Differentiation and Epidermal Proliferation During Murine Skin Development
Dermal EZH2 controls skin cell development and hair growth in mice.
research Gender Differences in Production and Circulating Levels of Sex Hormones and Their Impact on Aging Skin
Men and women experience skin aging differently due to changes in sex hormone levels with age.
research Dermal EZH2 Simultaneously Orchestrates Dermal Differentiation and Epidermal Proliferation During Murine Skin Development
Dermal EZH2 controls skin cell growth and differentiation in mice.
research Toxicity of the Pharmaceuticals Finasteride and Melengestrol Acetate to Benthic Invertebrates
Finasteride harms invertebrates' survival and burial ability.
research Relationship Between Androgenetic Alopecia and Cardiovascular Risk Factors According to BASP Classification in Koreans
Hair loss links to high blood pressure, high fat levels, and metabolic issues, suggesting early heart disease screening.
research Ageratum Conyzoides L. Extract Inhibits 5α-Reductase Gene Expression and Prostaglandin D2 Release in Human Hair Dermal Papilla Cells and Improves Symptoms of Hair Loss in Healthy Males and Females in an Open Label Pilot Study
Ageratum conyzoides L. extract may effectively and safely treat hair loss.
research Zinc in the Soil and Its Importance for Plants and Human Health: An Integrated Review
Zinc is essential for plant growth and human health, but many soils lack enough zinc, affecting crops and potentially leading to health problems.
research A Simple Screening Approach for Assessing Community Prevalence and Phenotype of Polycystic Ovary Syndrome in a Semiurban Population in Sri Lanka
A simple screening method found that 6.3% of women in a semiurban area in Sri Lanka have polycystic ovary syndrome, with most showing menstrual irregularities.
research Emerging Medication for the Treatment of Male Hypogonadism
New treatments for male hypogonadism are effective and should be personalized.
research Mutant Laboratory Mice With Abnormalities in Hair Follicle Morphogenesis, Cycling, and Structure: An Update
The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.
research Engineered Hair Follicle Mesenchymal Stem Cells Overexpressing Controlled-Release Insulin Reverse Hyperglycemia in Mice with Type 1 Diabetes
Genetically modified stem cells from human hair follicles can lower blood sugar and increase survival in diabetic mice.
research Shampoo Formulation
Shampoos clean hair mainly with surfactants and have added ingredients for extra benefits.
research Skin Disorders in Athletes: Professional and Recreational Sports
Athletes need effective management of skin disorders for their performance and well-being.
research Oral Cyclosporin Does Not Arrest Progression of Androgenetic Alopecia
Cyclosporin doesn't stop hair loss.
research The Rationale for Inhibiting 5α-Reductase Isoenzymes in the Prevention and Treatment of Prostate Cancer
Inhibiting 5α-reductase can help reduce prostate cancer risk and improve treatment.
research Combinatorial Expression of Cell Cycle Regulators Is More Suitable for Immortalization Than Oncogenic Methods in Dermal Papilla Cells
Using a combination of specific cell cycle regulators is better for safely keeping hair root cells alive indefinitely compared to cancer-related methods.
research The Immune Functions of Keratinocytes in Skin Wound Healing
Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.
research 17β-Estradiol Enhances Vascular Endothelial Growth Factor Production and Dihydrotestosterone Antagonizes the Enhancement via the Regulation of Adenylate Cyclase in Differentiated THP-1 Cells
Estrogen increases blood vessel growth factor production, while testosterone blocks this increase.
research Gender Difference in the Relationship Between Ferritin and Homeostasis Model Assessment of Insulin Resistance in Non-Diabetic Korean Adults
Iron levels are linked to insulin resistance in men and postmenopausal women, but not in premenopausal women.