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LY191704 is a compound that effectively blocks a specific enzyme involved in hormone conversion and could help treat enlarged prostate and hair loss.

Hirsute women have lower type 2 17β-HSD enzyme levels, which improve with treatment.

Finasteride-treated male rats' offspring had altered glucose metabolism, potentially increasing diabetes risk.

Two enzymes regulate androgen receptor activity, affecting treatments for androgen insufficiency and benign prostatic hyperplasia.

Male children's genital development issues can be caused by genetic mutations or environmental factors affecting hormone action.

Insufficient androgen action in male fetuses can cause genital development issues due to genetic mutations or environmental chemicals.

Human sebaceous glands contain enzymes that affect androgen production and may influence sebum production and acne.

A specific pathway involving AR, miR-221, and IGF-1 plays a key role in causing common hair loss.

The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.

Understanding how DHT works is important for diagnosing and treating hormone-related disorders.

Genetic differences within ethnic groups may affect prostate cancer treatment effectiveness.

Targeting lipid metabolism can help treat advanced, resistant cancers.

Researchers created immortal human skin cells with constant testosterone receptor activity to study hair loss and test treatments.

Androgens and a high-fat diet may increase the risk of severe COVID-19 in women with PCOS by upregulating certain proteins in the heart and kidneys.

Essential oils from Curcuma species, like turmeric, have compounds that can fight inflammation, cancer, and bacteria, and can also stimulate hair regrowth in bald males.

Different drugs can treat high male hormone levels in women, but they have various effects and some may harm a fetus.

The document concludes that hair loss is influenced by genetics and other factors, and while treatments like finasteride can help, they have limitations and side effects.

The review suggests that while many AKR1C3 inhibitors show promise for treating certain cancers, more research is needed to confirm their effectiveness in humans.

Excess androgens may cause PCOS, not just be a symptom.

Prenatally androgenized ewes can model increased hair diameter in women with PCOS.

Many potential alopecia treatments need more testing to confirm they promote acceptable hair growth with minimal side effects.

Finasteride for hair loss may cause persistent sexual symptoms, depression, anxiety, and lower quality of life.

Men using hair loss drugs like finasteride may experience sexual side effects like erectile dysfunction, but it's unclear who will be affected and when. Treating depression and sexual symptoms is suggested, as these men often have higher rates of both. More research is needed to understand why these side effects occur.

Hair diversity is influenced by complex genetics and environmental factors, requiring more research for practical solutions.

Men with common hair loss may have a higher risk of heart disease and diabetes, and should be checked for these conditions.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.

Plant extracts like Avicennia marina, Boehmeria nipononivea, and Camellia sinensis could potentially treat hair loss with fewer side effects than synthetic drugs.

Androgens may influence bladder cancer progression by affecting cellular behavior.

Sebocytes play a key role in controlling androgen levels in human skin.