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Finasteride affects brain stress and enzyme activity differently in various regions, possibly helping with liver-related brain issues.

Hair follicles are essential for skin health, aiding in hair growth, wound healing, and immune function.

Alternative treatments show promise for hair growth beyond traditional methods.

Finasteride helps hair growth but may cause sexual side effects and depression.

Researchers found new hair and nail genes, how hair reacts to UV, differences in white and pigmented hair growth, nerve changes in alopecia, treatments for baldness and alopecia, a toenail condition linked to a genetic disorder, and that nail fungus is more common in people with psoriasis.

Estrogens generally inhibit hair growth and improve skin quality, but their exact effects on hair follicles are complex and not fully understood.

Glucocorticoids and sex hormones affect skin health, with potential for targeted treatments to minimize side effects and treat skin conditions.

The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.

Hair aging is caused by stress, hormones, inflammation, and DNA damage affecting hair growth and color.

Altered metabolism can help control seizures by changing brain signaling and energy use, suggesting new treatments for epilepsy.

Ketogenic diet, neurosteroids, and HMGB1-TLR4 signaling pathway are potential targets for new epilepsy treatments.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.

The Trust tonic is more effective than minoxidil for treating hair loss.

Finasteride effectively treats male hair loss, improving growth and density.

A49T gene variant linked to higher prostate cancer risk, lower hormone levels, and slightly reduced balding risk.

5-alpha reductase inhibitors may have additional effects on cancer, mental health, heart health, and hormone levels beyond treating prostate enlargement.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

Extracts improve hair growth in alopecia.

Two enzymes regulate androgen receptor activity, affecting treatments for androgen insufficiency and benign prostatic hyperplasia.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.

Steroids, particularly estrogens and 5α-reductase inhibitors, affect blood vessel-related hair growth processes in hair follicle cells.

FCE 28260 is a stronger and longer-lasting inhibitor of 5α-reductase than finasteride, which may make it a better treatment for certain medical conditions.

The conclusion is that treatments like finasteride and minoxidil can prevent baldness progression and improve hair density, but more research is needed on other therapies.

Finasteride may increase depression by reducing brain cell growth.

The study created a new method to test drugs that affect hormone processing in skin.

The gene SDR5A1 is found in scalp hair of both hirsute and normal individuals, but it does not explain differences in hair growth.

Herbal extracts may help hair grow and could be an alternative to synthetic hair loss treatments.

Starting 5-alpha reductase inhibitors does not significantly increase the risk of rhabdomyolysis in older men, but is linked to a higher risk of muscle conditions.

Curcuma aeruginosa extract combined with minoxidil effectively treats male-pattern baldness.