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The review suggests younger men taking 1 mg finasteride report more side effects, including sexual, skin, metabolic, and psychological issues.

5α-Reductase inhibitors can help treat hair loss, acne, and prostate issues by reducing DHT levels.

Men over 66 taking medication for prostate enlargement have a higher risk of depression and self-harm, especially in the first 18 months of treatment.

New compounds show promise for treating hair loss, enlarged prostate, and prostate cancer, with some being more effective and having different side effects than current treatments.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Taking 5-alpha reductase inhibitors does not increase the risk of breast cancer in men.

Finasteride and dutasteride may cause metabolic issues like liver disease and diabetes.

Medicines for enlarged prostate may raise the risk of breast growth and tenderness but not breast cancer.

5-α-reductase inhibitors reduce prostate cancer risk but may cause sexual dysfunction and don't affect high-grade tumor or death rates.

Dutasteride works better than finasteride for hair loss, with both being safe to use.

5α-reductase inhibitors may worsen sexual drive and spontaneous erections but don't worsen existing erectile or ejaculatory problems.

Some hair loss and prostate drugs might increase the risk of diabetes and heart disease.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

FCE 28260 is a stronger and longer-lasting inhibitor of 5α-reductase than finasteride, which may make it a better treatment for certain medical conditions.

Reducing 5α-reductase activity helps endometrial cells differentiate, aiding pregnancy.

Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.

Ganoderma lucidum, a type of mushroom, may help treat enlarged prostate by blocking testosterone conversion.

Testosterone helps human pancreatic cells increase insulin release.

Tadalafil is effective for treating urinary symptoms in men with BPH.

Allopregnanolone is needed for certain brain processing issues caused by D1 dopamine receptor activation.

Hormones, especially androgens, play a key role in causing acne, and treatments like hormone control pills and hormone-blocking medications can help.

Men with early balding showed higher levels of certain genes linked to hair loss and possibly prostate cancer.

Understanding how androgens work is key for creating new treatments for prostate issues and hair/skin conditions.

Dutasteride is more effective than finasteride for hair loss treatment.

Different drugs can treat high male hormone levels in women, but they have various effects and some may harm a fetus.

Massaging the scalp with a cosmetic containing certain natural inhibitors can significantly regrow hair in men with pattern baldness.

Dihydrotestosterone and 5α-Reductase play a role in hair loss and prostate health, and finasteride can increase hair growth in men without affecting sperm production, but it doesn't work for postmenopausal women with hair loss.

We need to learn more about 5α-reductases and neuroactive steroids to safely make drugs targeting these enzymes.

New treatments for PCOS focus on insulin resistance and reducing testosterone levels, along with traditional hormone therapies.

Dutasteride, usually used for prostate issues and hair loss, could potentially treat Amyotrophic Lateral Sclerosis (ALS) due to its neuroprotective, antioxidant, and anti-inflammatory properties, but more testing is needed.