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This study found that a topical gel containing Minoxidil and Tofacitinib citrate showed promise for treating alopecia areata, with formulation F5 demonstrating effective drug release and stability in evaluations.

This case study demonstrated that off-label tofacitinib treatment led to full regrowth of scalp hair after 18 months in a patient with alopecia areata universalis, following unsuccessful therapies.

This article reviews potential applications and challenges of using the transfollicular route for drug delivery but does not present new clinical findings; it calls for further exploration and development in this field.

This study found that using a standardized protocol with microspheres of approximately 1.5 micrometers enhances penetration into hair follicles, particularly when skin is treated with cyanoacrylate skin surface stripping.

In this study, sublingual tofacitinib achieved a longer estimated half-life than oral administration in treatment-resistant alopecia areata patients, potentially supporting daily dosing; overall treatment response was modest.

In this study, researchers developed injectable micropore-forming hydrogels that enhance tissue adhesion strength and promote wound healing by allowing better cell infiltration and inducing hair follicle regeneration in skin incision wound models.

This review discusses the current procedure for follicular unit hair transplantation, emphasizing its natural and reproducible results, but does not report new clinical findings.

This study found that terbinafine prevented the invasion of keratin by Trichophyton mentagrophytes in experimental models replicating human dermatomycoses.

This study found that 3D microtissue models of dermal papilla cells can enhance the ability to induce hair-follicle neogenesis in vivo, offering potential for controlled cell production in follicle regeneration.

Touch domes in human skin are complex sensory structures not directly linked to hair.

Transethosomes improve drug delivery through the skin and show promise for treating various conditions.

In this study, FITC-labeled BSA nanocarriers delivered a model drug deeper into porcine ear skin hair follicles than the carriers themselves, as shown by confocal microscopy.

The flutamide-loaded hydrogel is a promising, skin-friendly treatment for acne and hair loss, potentially requiring less frequent application.

This article explains that proliferating trichilemmal tumors, originating in the hair follicle, can exhibit low-grade malignant potential, and recommends wide excision to minimize recurrence risk, but reports no new clinical findings.

This article reviews confocal microscopy findings in trichoepithelioma and desmoplastic trichoepithelioma, noting similarities with histological features, but it provides no new clinical results.

Tumescent local anesthesia is a safe, cost-effective method for outpatient liposuction.

This study found that telocytes in human scalp tissue were located around hair follicles and glands and may be involved in skin regeneration and homeostasis.

This study reports that daily topical application of a 0.05% tretinoin solution can eliminate the hair plugs and symptoms associated with trichostasis spinulosa.

In this study, TyroSpheres were used to encapsulate adapalene, increasing its solubility and enhancing skin distribution while reducing irritancy compared to a commercial formulation, indicating promise for acne treatment in ex vivo and in vitro settings.

This study found that encapsulating tamarillo polyphenols in cubosome nanoparticles protected them during digestion and enhanced the nutritional and antioxidant properties of yoghurt when used as a delivery system.

This review highlights the promising clinical outcomes of sacituzumab tirumotecan (sac-TMT), an antibody-drug conjugate for breast cancer that targets TROP2, demonstrating improved response rates and progression-free survival, with manageable safety concerns including primarily mild-to-moderate nausea and alopecia.

This study found that skin exposure to toluene diisocyanate in mice creates immune-recognition reservoirs in the skin's stratum corneum and hair follicles, potentially leading to sensitization and allergic reactions.

This study found that a conditioner treatment using 18-MEA combined with a specific cationic surfactant effectively restored hydrophobicity and reduced friction on damaged hair surfaces.

In this study, hydrophilic EG7 PTK-UR foams promoted better wound healing and tissue integration in a porcine model compared to more hydrophobic PTK-UR variants and a polyester-based alternative, while matching a collagen-based standard.

This case report presents an instance of tufted hair folliculitis in a woman treated with trastuzumab, highlighting a previously unreported skin side effect of this selective HER2 inhibitor.

In this study, researchers reported that cutaneous ultrasound may be a valuable tool in diagnosing and assessing inflammatory activity in tinea capitis, potentially guiding treatment decisions, especially in severe cases not apparent through clinical symptoms alone.