Tufted Hair Folliculitis in a Woman Treated with Trastuzumab
October 2010
in “
Targeted Oncology
”
TLDR Trastuzumab may cause tufted hair folliculitis as a side effect.
The document presented a case of tufted hair folliculitis, an inflammatory scalp condition characterized by scaling and pruritus, in a woman undergoing treatment with trastuzumab, a selective HER2 inhibitor. This was notable because, unlike HER1 inhibitors, HER2 inhibitors like trastuzumab were not previously associated with specific skin toxicities. This case was the first reported instance of tufted hair folliculitis as a side effect of trastuzumab therapy, highlighting a potential new dermatological side effect of this treatment.