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Human hair follicles have their own thyroid hormone system.

This review summarizes recent findings about the multi-site differentiation of tissue regulatory T cells, emphasizing the pivotal role of epigenetic remodeling, but it reports no new clinical results.

In this study, researchers analyzed over 5,000 T cells per sample using scRNA+TCR-seq technology and found that dual TCR Tregs are present in high proportions across various mouse tissues, showing unique TCR pairing patterns, V(D)J usage, and mRNA expression compared to single TCR Tregs.

In this study, partially purified apple polyphenols were found to inhibit preadipocyte differentiation in mouse cells by reducing GPDH activity and triglyceride accumulation.

The LTF gene may help predict and manage nonspecific orbital inflammation.

This study found that ginsenoside Rg3 up-regulates vascular endothelial growth factor expression in human dermal papilla cells and mouse hair follicles, suggesting its potential role in promoting hair growth.

This study observed that female patients with chronic telogen effluvium had significantly lower levels of total thiol, thiol-disulphide, and disulphide compared to healthy controls, indicating a disruption in oxidative stress balance.

In this study, GV-350 treatment over three months improved iron status and reduced the impact of Telogen Effluvium on quality of life among 20 iron-deficient women, with no adverse events reported.

This study found that the absence of Sgk3 in mice leads to impaired hair follicle maturation, characterized by reduced cell proliferation, increased apoptosis, and premature regression.

This study found that transfecting hair follicle stem cells with a PEI-DNA complex expressing hTERT stimulated hair growth in rats by inducing follicle neogenesis and promoting the anagen phase.

This study found that Neuregulin3 can influence the development and differentiation of mammary glands and epidermal features in mice, potentially by inducing c-Myc and altering cell proliferation and adhesion.

In this study, researchers developed a new prostate cancer imaging agent, a [99m Tc]tricarbonyl complex derived from finasteride, which demonstrated high radiochemical purity and significant uptake in the prostate of a rat model, suggesting its potential for noninvasive prostate cancer imaging.

This study found that low ferritin levels are associated with higher telogen ratios in women with diffuse hair loss, suggesting an important role of ferritin in telogen effluvium diagnosis.

This study introduced a simple and reliable in vitro assay capable of large-scale simultaneous screening of hair growth-promoting compounds using a 3D co-culture system of human dermal papilla and outer root sheath cells.

This study revealed distinct cellular and transcriptomic differences among various subtypes of cutaneous T-cell lymphoma, particularly highlighting characteristics unique to folliculotropic mycosis fungoides.

This study found that the Transdermal Delivery System efficiently delivers testosterone systemically and showed bioequivalent hormone concentrations to a known topical gel in healthy males.

A 4kb fragment of the desmocollin 3 promoter targets gene expression to specific skin and hair follicle areas.

In this study, researchers identified and examined males with 17 beta-HSD3 deficiency in a highly inbred Arab population, noting genetic findings and the progression of male characteristics despite being raised as females initially.

This study suggests that TGF-β 2 plays a critical role in hair follicle morphogenesis and may enhance the effectiveness of future cell therapies for hair regrowth using expanded dermal papilla cells.

This study found that plantar dermis matrix homogenate can partially restore the regenerative capacity of hair follicles impaired in culture, with CTHRC1 playing a critical role in this process.

This study found that lineage-restricted loss of p63 in murine thymic epithelial cells resulted in severe thymic hypoplasia and absence of hair follicles, indicating p63's critical role in thymic and hair follicle development.

This study found that estrogen, through estrogen receptors, can regulate the expression of the HOXC13 gene involved in hair follicle development, with MLL3 histone methylase playing a collaborative role.

3D spheroid cells effectively test hair growth compounds like Minoxidil.

In this case report, an 11-year-old girl with hypothyroidism was found to have Hashimoto thyroiditis after presenting with hair loss, short stature, and pubertal disturbances; the study emphasizes the importance of early diagnosis and personalized thyroid hormone therapy for better outcomes.

This study found that ARHGEF3 is crucial for hair follicle development in mice, as its absence leads to defects in placode compaction and impaired follicle downgrowth, highlighting its role in regulating cell shape rearrangements during embryogenesis.

This review discusses phenotypic differences in testosterone production between mice and humans with HSD17B3 deficiency and reports no new findings; the authors highlight potential pathways and enzymes involved in testosterone synthesis.

This study found that the progesterone metabolite 3α-THP increased the proliferation and gene expression of human glioblastoma cells, suggesting a role in tumor progression.

This study found that overexpressing the gene Thymosin β4 (Tβ4) can promote the growth and development of secondary hair follicle dermal papilla cells in cashmere goats, suggesting its potential as a target for increasing cashmere production.

The drug TGU was ineffective against small cell lung cancer and caused significant bone marrow suppression.

This study suggests that Thyroxine (T4) may promote key features of human skin wound healing, such as re-epithelialization and angiogenesis, in an ex vivo model.