Serum Plasma Thiol Evaluation in Chronic Telogen Effluvium Patients

June 2023 in “ Benha Journal of Applied Sciences ”

Amany A. Saleh, Mohamed Saber Hussein, A.M. Abdelrahman, Nehal Gamal Shafiek Mohammed

Chronic Telogen Effluvium CTE serum total thiol thiol-disulphide disulphide levels Telogen Effluvium TE oxidative stress thiol-disulfide balance chronic hair shedding hair loss

TLDR People with chronic hair shedding have lower antioxidant levels in their blood compared to healthy individuals.

The study "Serum Plasma Thiol Evaluation in Chronic Telogen Effluvium Patients" involved 60 patients with Chronic Telogen Effluvium (CTE) and 20 healthy volunteers. The research aimed to compare serum total thiol, thiol-disulphide, and disulphide levels in female CTE patients to those of healthy controls. The results showed that total thiol levels, thiol-disulphide, and disulphide levels were significantly lower in patients compared to controls. The study concluded that the pathophysiology of Telogen Effluvium (TE) is closely linked to oxidative stress, and the thiol-disulfide balance influences the development and prevention of oxidative stress, which is disrupted in TE.

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