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Women with female pattern hair loss have higher levels of certain androgens, suggesting increased androgen exposure to hair follicles.

The normal human prostate does not significantly affect blood DHT levels.

The document concludes that using LC-MS/MS for measuring androgens is more accurate than older methods, but it needs careful validation and standardized references to be most effective.

17α-estradiol is a safe estrogen that might protect the brain and doesn't cause feminization, needing more research for treating brain diseases.

Treatment during development affects hormone balance and sexual behavior in male rats.

Hair regrowth slows with age and can be affected by treatments that change enzyme activity in the skin.

Researchers created a mouse model of a type of rickets that does not cause hair loss.

Male rats have androgen receptors in their liver, which are different from proteins that bind estrogen.

These drugs cause hair growth without affecting testosterone or adrenal hormones.

bFGF, VEGF, and minoxidil decrease collagen production in hair cells, possibly affecting hair growth.

A specific protein in chicken embryos links early skin layers to feather development.

New steroid compounds effectively inhibit 5α-reductase and may treat hair loss.

Diagnosing hyperandrogenism in women is complex and requires accurate testing methods and consideration of SHBG levels.

Different factors like pH, gel type, and chemical enhancers affect how well hydrocortisone gets into hair follicles, and less hydrated skin doesn't work well with the test method.

Low doses of BPA can increase prostate growth and change hormone levels in adult rats.

Testosterone conversion to 5α-DHT may not be essential for its effects on the skin.

Changing the C-ring structure in certain compounds can make them better at blocking a specific human enzyme.

A new compound was created in 2010 that can control oil production when applied to the skin, and its effects are completely reversible after two weeks.

Reduced androgens linked to kinky hair disorder and hair loss; 5a-reductase inhibitors may help.

Transfollicular drug delivery is promising but needs more research to improve and understand it better.

Male pattern baldness may be caused by factors like poor blood circulation, scalp tension, stress, and hormonal imbalances, but the exact causes are still unclear.

Topical spironolactone cream doesn't cause hormone-related side effects in the body.

Flutamide, an antiandrogen, has minimal impact on female rat endocrine systems and does not significantly change their reproductive cycles.

Rat skin takes up and processes testosterone differently than other organs, with testosterone being more important for the skin than its metabolite 5α-DHT.

Baldness in men with prostate cancer is linked to higher levels of certain sex hormones, but chest hair density is not.

Two new compounds were found to effectively reduce hair growth in mice.

Scientists made new substances that can block an enzyme linked to prostate issues and hair loss, with potential for creating a new treatment.

Cyclosporine A therapy changes sex hormone levels differently in pre-menopausal and post-menopausal women with primary biliary cirrhosis.

Women with hyperandrogenism have higher androgen levels and lower SHBG, which may contribute to conditions like excessive hair growth and early puberty.

Dihydrotestosterone (DHT) is crucial for conditions like male-pattern baldness and acne, and measuring a byproduct, androstanediol glucuronide, is a better way to assess DHT's effects than DHT blood levels.