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The document concludes that using LC-MS/MS for measuring androgens is more accurate than older methods, but it needs careful validation and standardized references to be most effective.

New method measures female hair loss: Female Pattern Hair Loss Severity Index (FPHL-SI).

Hedgehog signaling is crucial for mammary gland development over hair follicles.

Certain herbal combinations in traditional Chinese medicine might be effective for treating hair loss, focusing on liver or stomach health.

The medications 5α-reductase inhibitors and spironolactone are generally safe for breast cancer patients on endocrine therapies and do not significantly increase breast cancer risk.

DHEA may help with sexual function when used intravaginally by menopausal women but is similar to hormone therapy in other aspects and might cause more side effects like acne and hair loss.

A specific gene change plus an additional mutation in the same gene cause hereditary trichilemmal cysts.

Blocking TSLP reduces skin inflammation and cell overgrowth in psoriasis.

Spironolactone, a heart and liver drug, has new uses including cancer treatment, viral infection prevention, and skin condition improvement.

The article concludes that correctly diagnosing systemic causes of hair loss requires a detailed clinical evaluation and a systematic diagnostic approach.

Canine epidermal neural crest stem cells could be a promising treatment for spinal cord injuries in dogs.

New patents show progress in developing drugs targeting the Wnt pathway for diseases like cancer and hair loss.

Blocking 5α-reductase can harm memory and brain structure, and increase harmful brain changes in male mice used for Alzheimer's disease research.

Testosterone helps human pancreatic cells increase insulin release.

Different types of fibroblasts play various roles in kidney repair and aging, and may affect chronic kidney disease outcomes.

Breast cancer skin metastases are rare, look different, and can be confused with other skin issues, so a biopsy is needed for accurate diagnosis.

11α-Hydroxyprogesterone is changed into different substances by certain enzymes and may play a role in prostate cancer.

Inhibiting 5α-reductase increases progesterone levels in late pregnant mares.

Acne is a chronic skin condition not caused by poor hygiene or diet, and it requires long-term treatment and patient education.

Chinese medicine may help treat hair loss by affecting genes and enzyme activity.

Biotin helps regulate proteins in the blood, which may explain its role in hair growth.

The skin protects the body, regulates temperature, senses touch, and makes vitamin D.

Finasteride may affect PNMT, causing side effects.

Steroid hormones are crucial for body functions and have various medical uses, but their misuse can lead to dependence.

Minoxidil does not work to inhibit lysyl hydroxylases in newborn mouse lungs.

Certain genetic variations are linked to higher liver enzyme levels in patients treated for chronic hepatitis C with specific drugs.

Early balding, premature graying, and hair thinning can predict heart disease in young Asian males.

Patients with advanced breast cancer and high hormone receptor levels who had surgery for ovarian/pelvic metastases lived longer, especially if they had high estrogen receptor levels.

Female pattern hair loss involves thinning hair on crown and frontal scalp, diagnosed by hair ratio, and treated with minoxidil, antiandrogens, or hair transplantation.

Taking Saw palmetto and Pygeum africana can change the levels of certain steroids in urine, which could cause confusion in doping tests.