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Immune cells are essential for early hair and skin development and healing.

Women with PCOS have higher levels of certain blood clotting factors, suggesting a greater risk of cardiovascular issues.

Brown Adipose Tissue (BAT) could potentially treat Polycystic Ovary Syndrome (PCOS) by controlling energy balance and lipid homeostasis, but more human research is needed.

Removing myelin protein zero-like 3 in mice leads to better metabolism and resistance to obesity.

Female mice with disrupted 5α-reductase 1 had significant metabolic issues, including stress response problems, insulin resistance, liver fat buildup, and obesity.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Fat cells are important for healthy skin, hair growth, and healing, and changes in these cells can affect skin conditions and aging.

People with PCNT mutations often develop severe insulin resistance and early-onset diabetes during childhood or adolescence.

Different sPLA2 enzymes affect immunity, skin and hair health, reproduction, and may be potential targets for therapy.

Women with PCOS in Sicily show different levels of metabolic problems depending on their PCOS type, with obesity and abnormal lipid profiles being common.

Deleting the Far2 gene in mice causes sebaceous gland issues and patchy hair loss.

Blood removal and birth control pills both helped with hormone levels in women with PCOS, but birth control was better for regular periods and blood removal had fewer side effects.

More research is needed before using brown fat to treat polycystic ovary syndrome.

Metformin and rosiglitazone both improved insulin use and hormonal symptoms in women with PCOS.

People with alopecia areata have higher insulin resistance.

Darkened knuckles can be an early sign of insulin resistance.

Many young Egyptian women with PCOS also have fatty liver disease, especially if they are overweight and insulin resistant.

Skin health and repair depend on the signals between skin stem cells and their surrounding cells.

Fat cells are important for tissue repair and stem cell support in various body parts.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

Taking DHEA for a year is generally safe for postmenopausal women but may cause acne and more facial hair without improving metabolism or aging.

Isotretinoin improves severe acne without changing androgen or insulin levels but may increase body weight and triglycerides.

The timing of when the gene Bmal1 is active affects aging and survival, with its absence during development, not adulthood, leading to premature aging.

Mice studies show that Protein Phosphatase 2A is crucial for cell growth, development, and disease prevention.

People with alopecia are at higher risk for heart disease and have more heart-related risk factors.

Plant steroid hormones show growth, health, and medicinal benefits in various organisms, including potential for treating diseases.

Kolaviron and quercetin may help treat prostate issues.

Increasing sebum production might help reduce fat and improve metabolism.

The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.

Foxn1 is important for fat development, metabolism, and wound healing in skin.