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The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Animals that change color with the seasons mainly do so in response to daylight changes, but climate change is causing camouflage problems that may require evolutionary changes.

The article concludes that better understanding gene regulation related to seasonal changes can offer insights into the mechanisms of seasonal timing in mammals.

Hidradenitis suppurativa is caused by genetic factors, inflammation, bacteria, hormones, and lifestyle factors like obesity and smoking.

Janus kinase inhibitors are promising drugs for treating autoimmune and inflammatory diseases.

Genetically modified plants could be an important source of omega-3 fats to meet global needs.

Drug repositioning is becoming more targeted and efficient with new technologies, offering personalized treatment options and growing interest in the field.

Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.

Skin organoids are a promising new model for studying human skin development and testing treatments.

Gene network oscillations inside hair stem cells are key for hair growth regulation and could help treat hair loss.

Tissue stiffness affects hair follicle regeneration, and Twist1 is a key regulator.

The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.

Thyroid hormones and androgens affect gene expression in frog reproductive organs differently between males and females.

New protein changes may be involved in the immune attack on hair follicles in alopecia areata.

Different types of fibroblasts play various roles in kidney repair and aging, and may affect chronic kidney disease outcomes.

Researchers found four genes that could help diagnose severe alopecia areata early.

Different proteins are linked to the varying thickness of sheep and goat hair types.

Sebaceous glands can heal and regenerate after injury using their own stem cells and help from hair follicle cells.

Pangolins have lost some skin-related genes, but kept others, leading to their unique scales and skin features.

CD4+ skin cells may be precursors to basal cell carcinoma.

Immune cells are crucial for hair growth and preventing hair loss.

Different immune responses cause hair loss in scalp diseases, with unique patterns in scalp psoriasis possibly protecting against hair loss.

Keratin-associated proteins have ancient origins and were used for different purposes before being adapted for hair in mammals.

Researchers identified genes that may affect hair growth in Cashmere goats.

New treatments for hair loss should target eight main causes and use specific plant compounds and peptides for better results.

Psoriasis may be chronic because it lacks certain immune system controls that prevent overreaction.

Immune cells are essential for skin regeneration using biomaterial scaffolds.

Long-haul COVID can cause lasting symptoms affecting many body systems and may be linked to ongoing inflammation and immune system issues.

Reactive oxygen species (ROS) help control plant growth and development.