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This article describes the synthesis of novel polyamine-modified minoxidil analogs and conjugates to potentially enhance minoxidil's biological activity, selectivity, and water solubility, but reports no new biological results.

This review found that adding immune checkpoint inhibitors to cancer treatment regimens likely increases the incidence of specific drug-related skin toxicities in adult Asian patients, highlighting the need for careful monitoring and management strategies.

This study tested the acute toxicity of Ficus platyphylla methanol leaf extract in Wistar rats and found no mortality or significant liver enzyme changes at doses up to 5000 mg/kg, suggesting a high margin of acute safety and supporting its traditional use under short-term exposure.

This study found that the methanol leaf extract of Ficus platyphylla demonstrated a high margin of acute safety in Wistar rats, showing minimal risk under short-term exposure with no mortality at doses up to 5000 mg/kg and no significant changes in liver enzyme activities.

This review describes how cutaneous toxicity from kinase inhibitors, immune checkpoint inhibitors, and chemotherapeutics could potentially serve as a biomarker for anticancer treatment efficacy, but highlights the need for more extensive research to confirm this association.

This study in female beagle dogs found that long-term exposure to oral contraceptive steroids resulted in significant reproductive and mammary gland changes, with the relevance to human tumor risk remaining uncertain.

This study demonstrates a method to noninvasively assess lipid classes in rodent sebum via high-field proton NMR, observing significant lipid reductions in rats treated with an SCD1 inhibitor.

This review reports various ethnomedicinal uses, phytochemical components, and potential pharmacological effects of Eclipta alba, highlighting benefits like wound healing and neuroprotection, though it underscores the need for further mechanism-based studies and clinical trials.

This review discusses the ethnobotanical uses and phytochemistry of Plumbago zeylanica L., highlighting its potential pharmacological benefits for conditions such as diabetes and cardiovascular disorders, but reports no new experimental findings.

In this study, a combined therapy of nicotinamide and green tea polyphenols was reported to improve EGFR inhibitor-related skin toxicity and patient quality of life, suggesting it merits further investigation.

This research discusses potential cancer vaccine strategies using cell-based and DNA vector-based approaches, and suggests targeting the v3 splice variant of thioredoxin reductase 1 to inhibit cancer cell motility and metastasis formation.

This study found that a developed nanostructured lipid carrier formulation of tea seed oil can effectively stimulate hair growth and reduce the oily feeling associated with direct application.

This chapter reports an organ culture method that permits mouse embryonic skin tissues to develop similarly to in vivo conditions, revealing that epidermal growth factor inhibits hair follicle formation.

This review discusses the toxic effects and mechanisms of platinum compounds in cancer treatment, emphasizing the need for new compounds with different mechanisms of action; it reports no new clinical results.

This review discusses the pharmacological benefits and chemical compounds of the Sophora genus, noting its traditional use and wide pharmacological actions, but reports no new clinical results.

This study found that ethyl acetate extract from peanut stems demonstrated very strong antioxidant properties and moderate cytotoxic activity against MCF-7 cell lines in in-vitro and in-silico settings.

Microfluidic models improve testing for aging, wound healing, and oral tissue, reducing animal testing.

This review of Cynoglossum amabile, a traditional Chinese and ethnomedicine, provides insights into its uses, chemical components, biological activities, and toxicity. Highlighting its market potential, the study underscores the importance of indigenous knowledge in drug development despite noted hepatotoxic risk linked to its pyrrolizidine alkaloids.

This study found that neither caffeine nor N,N-dimethylglycine treatments were toxic to balding or nonbalding dermal papilla cells and could stimulate calcium influx, indicating treatment responsiveness.

This review discusses the cosmetic use and safety of Hypericum Perforatum Extract and Oil, finding that current data are insufficient to support their safety in formulations due to a lack of comprehensive testing.

This review explores the biological applications and pharmacokinetics of decursin, a compound isolated from Angelica gigas, highlighting its potential neuroprotective, anti-inflammatory, and anticancer properties based on in vitro and in vivo studies.

This paper discusses various toxicological properties of diphenyl cresyl phosphate, highlighting its low acute toxicity, potential neurotoxicity linked to o-cresyl phosphate content, and the lack of data for inhalation exposure, but presents no new experimental findings.

The researchers described a chip-based bioreactor platform for dynamic perfusion, which may enhance in vitro skin models by introducing mechanical shear stress and extending culture periods.

This review reports on the dual aspect of fullerene in skincare, highlighting its beneficial antioxidant properties as well as potential toxicity and skin cell reactions, while identifying areas for future research.

This viewpoint essay discusses the potential of fullerene C60 derivatives as novel treatment agents in dermatology, highlighting their ability to act as both radical scavengers and oxygen radical generators.

This review discusses the use of human and animal-derived placental and umbilical extracts in cosmetics, highlighting insufficient data to establish their safety and recommending they should not have metabolic or endocrine activity.

This study reports that novel core-ABS nanocarriers efficiently loaded with dexamethasone and finasteride show potential for dermal drug delivery, exhibiting non-toxic interactions with human keratinocyte cells and skin penetration.

This review explores nano-quercetin formulations to enhance the solubility, stability, and targeted delivery of quercetin, highlighting its potential efficacy in treating cancer, inflammation, metabolic diseases, and tissue regeneration, though challenges in biocompatibility, toxicity, and production remain, per this source.

This study demonstrated that adenosine triphosphate may prevent vandetanib-induced skin toxicity in rats, suggesting potential for further research in other animal models and humans.

This symposium reviewed strategies to advance stalled drug molecules, discussed common regulatory hurdles, and explored options for repurposing drugs, but it reported no new research findings.