research Hyperandrogenism and Menstrual Imbalance Are the Best Predictors of Metformin Response in PCOS Patients
High levels of male hormones and irregular periods best predict how well PCOS patients will respond to metformin treatment.
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research Proxalutamide Improves Inflammatory, Immunologic, and Thrombogenic Markers in Mild-to-Moderate COVID-19 Males and Females: An Exploratory Analysis of a Randomized, Double-Blinded, Placebo-Controlled Trial Early Antiandrogen Therapy with Proxalutamide
Proxalutamide improved blood markers related to inflammation, immune response, and clotting in COVID-19 patients, potentially reducing hospitalizations.
research Lack of Association Between Clinical and Biochemical Hyperandrogenism in Patients With Polycystic Ovary Syndrome
Clinical signs of excess male hormones and actual hormone levels in the blood do not always match in women with polycystic ovary syndrome.
research 46, XY 5-Alpha Reductase Deficiency in a 36-Year-Old Phenotypic Female Patient
A 36-year-old person with a female appearance but male chromosomes was diagnosed with a rare enzyme deficiency affecting sexual development.
research Serenoa Repens Induced Erectile Dysfunction: Underdiagnosis and Phytovigilance
Saw palmetto may cause erectile dysfunction and needs better safety monitoring.
research Androgenetic Alopecia: A Review and Emerging Treatments
Hair loss, known as Androgenetic Alopecia, is often caused by hormones and can be diagnosed using noninvasive techniques. Treatments include topical minoxidil and oral finasteride, with new treatments being explored. There may also be a link between this type of hair loss and heart disease risk.
research The Impact of Physical Activity in a Case of Polycystic Ovary Syndrome
Physical activity significantly improved symptoms of PCOS in a patient.
research The Impact of Levothyroxine on Thyroid Autoimmunity and Hypothalamic–Pituitary–Thyroid Axis Activity in Men with Autoimmune Hypothyroidism and Early-Onset Androgenetic Alopecia
Levothyroxine is less effective in men with early-onset male-pattern baldness.
research Ethosomes: An Exciting and Promising Alcoholic Carrier System for Treating Androgenic Alopecia
Ethosomes are a promising method for treating hair loss by delivering drugs directly to the scalp.
research Depression, Higher Level of Tension Induction, and Impaired Coping Strategies in Response to Stress in Women with PCOS Correlate with Clinical and Laboratory Indices of Hyperandrogenism and Not with Central Obesity and Insulin Resistance
Women with PCOS have more depression and stress due to high androgen levels, not obesity or insulin resistance.
research Serum Gelsolin Levels in PCOS-Related Androgenetic Alopecia
Women with PCOS and hair loss have lower levels of the protein gelsolin in their blood.
research Elevated DHEAS and Acute Hair Loss in an Adult Male with Trichorhinophalangeal Syndrome Type 1: A Case of Male PCOS
A 21-year-old male with a rare genetic disorder experienced sudden hair loss and high DHEAS levels, likely due to a condition similar to PCOS, usually seen in women.
research A Rare Case of Adolescent Girl with Beard-PCOS with a Difference: HAIR-AN Syndrome
A 16-year-old girl with HAIR-AN syndrome was treated with lifestyle changes and medications to manage her condition.
research A Case of Successful Treatment with Unilateral Oophorectomy in a Patient with Resistant Polycystic Ovary Syndrome
Removing one ovary helped treat a woman's severe PCOS symptoms when medicine didn't work.
research Postmenopausal Virilization: Rare Case of an Ovarian Tumor Not Easily Identified on Imaging
An ovarian tumor caused a woman's male-like symptoms, which improved after surgery.
research Case Report: Exceptional Association of Leydig Cell Ovarian Tumor and Primary Hyperparathyroidism in a Postmenopausal Patient
A woman with a rare ovarian tumor and hyperparathyroidism improved after surgery, highlighting the need for reporting unusual cases to understand and manage rare diseases.
research Quality of Life, Psychopathologic Symptoms, and Personality Disorders in Subjects with Androgenetic Alopecia
Alopecia linked to higher anxiety and personality disorders.
research Pituitary Effects of Metformin in Men With Early-Onset Androgenic Alopecia
Metformin reduces certain hormone levels in men with early-onset hair loss.
research Endocrine Treatment of Transsexual Persons: An Endocrine Society Clinical Practice Guideline
The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.
research Management of Sexual Dysfunction in Postmenopausal Breast Cancer Patients Taking Adjuvant Aromatase Inhibitor Therapy
Non-hormonal treatments should be used first for sexual dysfunction in postmenopausal breast cancer patients on aromatase inhibitors, with hormones as a second option.
research Care of the Transgender Patient: The Role of the Gynecologist
Gynecologists should provide comprehensive care for transgender patients, including mental health evaluation, hormone therapy, and surgical options, while monitoring for side effects and ensuring patient safety.
research Androgens and Ovarian Function: Translation from Basic Discovery Research to Clinical Impact
Androgens are important for female fertility and could help in IVF treatment, but also play a role in causing PCOS.
research Intracrine and Myotrophic Roles of 5α-Reductase and Androgens
Muscles can make their own androgens, which may help muscle growth.
research Consequences of Anabolic-Androgenic Steroid Abuse in Males: Sexual and Reproductive Perspective
Using anabolic-androgenic steroids can harm men's reproductive health and increase the risk of heart problems and death.
research Practical Geriatrics: Men's Sexual Health After Midlife
Older men should openly discuss sexual health with doctors to improve their quality of life.
research Female Pattern Hair Loss: An Update
Female pattern hair loss has multiple causes and treatments, with new therapies showing promise.
research 11-Oxyandrogens in Adolescents With Polycystic Ovary Syndrome
Girls with PCOS have higher levels of certain androgens, which are linked to excess hair growth, but these androgens don't help diagnose PCOS.
research What Does the Research Say About Androgen Use and Cerebrovascular Events?
Androgen use may increase the risk of stroke, but more research is needed.
research Ovarian Stromal Hyperthecosis and Hyperandrogenemia Refractory to Hormonal Suppression
Removing both ovaries may better treat increased male hormone levels and related symptoms in postmenopausal women when hormone therapy doesn't work.
research The Interplay of Oxidative Stress and Immune Dysfunction in Hashimoto’s Thyroiditis and Polycystic Ovary Syndrome: A Comprehensive Review
Oxidative stress and immune dysfunction are linked to both Hashimoto's thyroiditis and polycystic ovary syndrome, with diet and specific treatments important for managing these conditions.