15 citations
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February 2014 in “Toxicology Letters” This study found that osthole, a coumarin derivative, demonstrated significantly higher skin accumulation and potential skin irritation compared to coumarin, which showed negligible alterations in protein biomarkers.
1 citations
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January 2005 in “Side effects of drugs annual” This chapter reviews various dermatological drugs and treatments, highlighting adverse effects, with no new clinical findings reported.
January 2026 in “Dermatologic Therapy” This study found that a novel topical dutasteride lotion, FOL100, demonstrated excellent safety, tolerability, and usability with promising signs of clinical benefit for mild-to-moderate male pattern baldness.
March 2025 in “JEADV Clinical Practice” This article explores the role of ketoconazole shampoo in hair care beyond treating dandruff and seborrhoeic dermatitis, suggesting it may reduce hair shedding and chronic scalp inflammation, potentially complementing treatments for androgenetic alopecia.
January 2025 in “International Journal of Research and Innovation in Applied Science” This study aimed to enhance the skin penetration of minoxidil by encapsulating it in glycerosomal vesicles, offering a potential improvement in transdermal drug delivery for treating androgenetic alopecia. Results of the investigation were not reported.
March 2026 in “Seven Editora eBooks” This study systematically reviewed the use of topical testosterone products such as creams, gels, and patches, finding they effectively raise serum testosterone but pose significant systemic risks like acne and gynecomastia, necessitating careful medical oversight.
June 2025 in “Pharmaceutics” This study found that ethosomes containing 30% ethanol slightly improved the targeting of dutasteride to hair follicles in vitro, with a higher targeting factor compared to dried ethosomes and controls after 24 hours on porcine skin.
March 2025 in “Archives of Dermatological Research” This study found that combined microneedling with minoxidil significantly improved hair count and diameter in patients with androgenetic alopecia, although more mild adverse events were reported compared to minoxidil alone.
1 citations
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July 2021 in “Chemical & pharmaceutical bulletin/Chemical and pharmaceutical bulletin” This study found that rubbing significantly increased skin permeation of caffeine but not rhododendrol, with the direction of rubbing playing a crucial role in caffeine's enhancement.
January 2026 in “Dermatologic Therapy” This review indicates that while microneedling shows potential for managing androgenetic alopecia, particularly in combination with other treatments, the existing evidence is of low to moderate quality, and more robust trials are needed to confirm its clinical efficacy and safety.
June 2024 in “Majallah-i dānishgāh-i ̒ulum-i pizishkī-i Kirmān.” This study evaluated enhancers to improve skin absorption of topical cetirizine for androgenic alopecia treatment and found eucalyptus and Tween 80 most effective, while propylene glycol had the weakest effect.
November 2024 in “Journal of Drugs in Dermatology” This article highlights the need for a comprehensive review of injectable minoxidil for hair loss, as existing treatments primarily focus on topical and oral forms of the medication.
This study identified rare nucleotide substitutions in the SLC39A4 gene in children with acrodermatitis enteropathica, suggesting a genetic component to the disease's etiology.
3 citations
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August 2021 in “Journal of fiber science and technology” This study found that chitin nanofibrils prepared by the aqueous counter collision process exhibited superior emulsifying properties for stabilizing oil droplets in Pickering emulsions compared to cellulose nanofibrils.
93 citations
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January 2007 in “Skin Pharmacology and Physiology” In this study, caffeine applied in a shampoo penetrated hair follicles faster and more effectively than through the skin surface within the first 20 minutes.
67 citations
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January 2007 in “Climacteric” This article discusses the impact of estrogens on skin aging, highlighting the potential benefits and unresolved effectiveness of alternatives like phytoestrogens and selective estrogen receptor modulators; it reports no new clinical results.
34 citations
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July 2010 in “Expert Opinion on Drug Delivery” This review highlights the need for methodologies to understand and quantify drug penetration into hair follicles as significant drug pathways, noting this area lacks comprehensive articles and reports no new results.
25 citations
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January 1978 in “JAMA” This case report describes a 45-year-old woman who developed Cushing's syndrome and hirsutism after using topically applied desoximetasone (Topicorte).
20 citations
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August 2021 in “Journal of Cosmetic Dermatology” This review examines the potential use and challenges of topical cannabinoids for skin diseases and hair growth, highlighting limited clinical data on their efficacy and safety.
11 citations
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April 2015 in “EBioMedicine” This research highlights that JAK inhibitors, such as baricitinib, may effectively reverse symptoms of alopecia areata by targeting specific immune pathways, though safety and efficacy require further investigation.
8 citations
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December 2024 in “Frontiers in Medicine” In this study, different treatments on ex vivo skin models effectively simulated varying levels of skin damage, demonstrating the value of these models in testing skin repair products and studying how a compromised skin barrier affects viral penetration.
7 citations
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August 2024 in “JAAD reviews.” This review reports that low-dose oral minoxidil can cause hypertrichosis due to increased systemic absorption, and highlights the importance of patient-centered care to manage the psychosocial impacts of this side effect effectively.
6 citations
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January 2017 in “Dermato-endocrinology” This study found that androsterone glucuronate (ADT-G) was the only androgenic metabolite sensitive to detecting differences between adult women with acne and controls, and its levels decreased with systemic treatment.
2 citations
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December 2022 in “Journal of toxicologic pathology” This review outlines the histological structures of the skin, highlighting species and regional differences in dermal absorption and obstacles encountered in toxicological assessments due to epidermal thickness variability, contact dermatitis reactions, and stem cell vulnerabilities.
March 2026 in “Preprints.org” This study reviewed evidence for six minimally invasive treatments for androgenetic alopecia, finding consistent support for platelet-rich plasma and topical finasteride, while other options like microneedling and intradermal dutasteride showed promise but need further and standardized research.
February 2026 in “Cureus” This case report suggests that crisaborole may be an effective alternative treatment for alopecia areata in pediatric patients, showing significant hair regrowth after two weeks in a 10-year-old girl.
March 2022 in “Brazilian Journal of Health Review” This study suggests that COVID-19 infection can lead to telogen effluvium, typically occurring 3-6 months post-infection, potentially linked to the virus's inflammatory and anticoagulation effects.
November 2019 in “Harper's Textbook of Pediatric Dermatology” This article reviews Netherton syndrome, focusing on its genetic basis, clinical presentation, and treatment options, and reports no clinical results; the authors mention potential benefits of targeted therapies and gene therapy.
April 2023 in “Journal of Investigative Dermatology” In this study, a novel AR protein degrader was shown to reverse DHT-induced hair regrowth delay in a mouse model of androgenetic alopecia, with minimal circulation and potential side effects.
November 2013 in “Journal of Mazandaran University of Medical Sciences” This study found that a topical solution of caffeine and minoxidil 2.5% was more effective in treating androgenetic alopecia than minoxidil 2.5% alone.