January 2016 in “대한피부과학회지” This case report describes two patients experiencing a bortezomib-induced skin eruption as multiple plaques on the trunk, with the lesions resolving spontaneously in about a week.
2 citations
,
May 2020 in “The journal of investigative dermatology/Journal of investigative dermatology” This study describes a family where a TP63 mutation was linked with prominent alopecia and mild ectodermal dysplasia features.
24 citations
,
October 2018 in “JAAD Case Reports” This paper reviews the challenges of treating alopecia areata affecting eyelashes and discusses the risks associated with traditional therapies; it reports no new clinical results.
24 citations
,
July 1983 in “Clinical and Experimental Dermatology” Tigason improved hair growth in a boy with monilethrix without side effects.
6 citations
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January 2021 in “Frontiers in Immunology” This study found that deficiency in TLR3/TRIF signaling reduced inflammation and protected mice against postoperative ileus, suggesting potential for TLR3 antagonism as a preventive approach in humans.
April 2024 in “Indian Journal of Paediatric Dermatology” This case report highlights a rare association between congenital triangular alopecia and vitiligo, noting that treatment with tofacitinib improved the patient's vitiligo but not the alopecia.
1 citations
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September 2025 in “Physiologia” This study found that systemic ovalbumin–aluminum sensitization followed by cutaneous challenge in mice induced thermal hyperalgesia, increased spinal cord gliosis, and sprouting of nociceptive fibers, along with elevated mast cell and nerve profile densities in the skin compared to controls.
25 citations
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June 2017 in “Neuropharmacology” This study observed that overexpressing TSPO in the hippocampal dentate gyrus of mice led to significant anxiolytic and antidepressant-like effects, potentially mediated by increased allopregnanolone synthesis.
18 citations
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April 2016 in “Molecular Genetics and Genomics” This study suggests that thymosin beta 4 may regulate hair growth by influencing VEGF and MMP-2 levels through the Wnt/β-catenin/Lef-1 signaling pathway in mouse models.
April 2018 in “The Journal of urology/The journal of urology” This study identified several patient-specific factors that can predict both the likelihood of undergoing and failing a post-TURP void trial, aiding in the selection of candidates for immediate assessment.
9 citations
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May 2014 in “BMC medical genetics” In this case report, the authors suggest that a novel enhancer element's translocation near the TRPS1 gene may contribute to the TRPS phenotype, expanding understanding of the syndrome's genetic basis.
March 2023 in “Archives of Physical Medicine and Rehabilitation” This pilot study suggests that high-dose testosterone plus finasteride improved knee extensor strength and muscle size in men with impaired gait after chronic incomplete spinal cord injury.
1 citations
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April 2023 in “Indian Journal of Dermatology Venereology and Leprology” This case report describes a young adult with primary follicular mucinosis, successfully treated with topical tacrolimus, resulting in resolution without sequelae.
11 citations
,
October 2019 in “Journal of Cancer Immunology” This article discusses the role of external beam radiotherapy as a primary treatment method for cancer and reports no new clinical findings.
2 citations
,
September 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” This study demonstrated that ablation of individual somatostatin-expressing interneurons increased activity in nearby neurons of the mouse motor cortex during motor learning.
11 citations
,
October 2005 in “Toxicological Sciences” In this study, mouse skin exposed to cigarette smoke condensate exhibited increased epidermal thickness and ODC expression, with some changes persisting after exposure ended, suggesting potential for tumor promotion and measurement discrimination.
November 2025 in “Biomedicines” This study found that the JAK1 inhibitors baricitinib and abrocitinib significantly reduced mechanical alloknesis in a murine model of atopic dermatitis, whereas the JAK2 inhibitor AZ960 had no effect.
2 citations
,
January 2000 in “Journal of Toxicologic Pathology” This study identified a single autosomal recessive gene responsible for hypotrichosis in a mutant rabbit strain, affecting hair growth and causing epidermal and hair follicle abnormalities.
In this study with mice, simultaneous inactivation of Smad4 and PTEN genes led to rapid development of invasive forestomach squamous cell carcinomas, mirroring human esophageal SCCs.
3 citations
,
September 1973 in “Archives of dermatology” This study reports that daily topical application of a 0.05% tretinoin solution can eliminate the hair plugs and symptoms associated with trichostasis spinulosa.
August 1994 in “Molecular Endocrinology” This study found that AtT-20 pituitary cells with higher cAMP-dependent kinase activity had larger calcium currents and significantly increased beta-endorphin release compared to cells with lower kinase activity.
21 citations
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March 2015 in “Neurological Sciences” This study reports that a novel frameshift mutation in the HTRA1 gene in a CARASIL pedigree led to reduced HTRA1 protein and increased TGF-β1 expression, potentially causing severe CARASIL and peripheral small arterial disease.
1 citations
,
March 2022 in “Journal of Dermatological Science” This study concluded that overexpressing TERT and BMI1 in cultured human dermal papilla cells extended their lifespan and enhanced their ability to induce hair growth in mice.
2 citations
,
March 2025 in “Cancer Gene Therapy” This study found that elevated androgens in the brains of glioblastoma patients are produced by tumor cells, and overexpressing Sirt1 reduces these levels, thereby delaying tumor progression more effectively than conventional therapy in mouse models.
21 citations
,
January 2005 in “Pediatric Dermatology” An 8-year-old girl with vitiligo developed extra hair growth on her knee after using tacrolimus ointment.
January 2015 in “Elsevier eBooks” This study suggests that targeting the endocannabinoid system through pharmacological interventions may help reduce compulsive hair-pulling in individuals with trichotillomania.
October 2019 in “European heart journal” This study found that androgen deprivation therapy is associated with an increased risk of acquired long-QT syndrome and Torsades de Pointes, particularly highlighting enzalutamide's greater association with sudden death compared to other therapies.
July 2022 in “Journal of Investigative Dermatology” This study found that a TYK2 inhibitor, BMS-986202, may restore immune privilege in hair follicles and promote hair regrowth in a humanized alopecia areata mouse model by inhibiting IL-12-mediated signaling.
88 citations
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August 2019 in “Frontiers in immunology” This review discusses the role of tyrosine kinase signaling pathways in autoimmune and inflammatory skin diseases and reports no new clinical results, highlighting ongoing research into small-molecule tyrosine kinase inhibitors as potential treatments.
April 2023 in “Revista colombiana de reumatología” In this study, a 24-year-old patient with severe alopecia areata showed an excellent clinical response to the JAK inhibitor tofacitinib after one month, following unsuccessful previous treatments.