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Skin cells release substances important for healing and fighting infection, and understanding these could improve skin disorder treatments.

Hormones affect skin aging, and treatments targeting hormonal balance may improve skin health.

Biologic therapies can cause various adverse events, but allergy/immunology clinicians can manage them.

Some drugs may help treat both COVID-19 and radiation injury.

Allopregnanolone can reduce gut inflammation and normalize neurotransmitter levels after finasteride withdrawal.

Managing oxidative stress might help treat low testosterone and related chronic diseases in aging men.

Mutations in the glucocorticoid receptor gene cause reduced sensitivity to glucocorticoids and may lead to poor response to treatment.

Synthetic antioxidants are effective, cheap, and stable, with some like zinc and cholecalciferol reducing child and cancer deaths, but the safety of additives like BHA, BHT, TBHQ, and PEG needs more research.

Deferasirox combined with sorafenib reduces liver cancer risk and lessens treatment side effects.

Free fatty acids in sebum boost skin's defense against acne by increasing antimicrobial peptides.

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.

The guide explains how to study human skin fat cells and their tissue, aiming to improve research and medical treatments.

Alopecia areata is an autoimmune hair loss condition treated with corticosteroids, and histologic confirmation is the best diagnosis method.

*Acorus calamus* has many medicinal benefits but needs more safety research.

Applying an extract from Perilla frutescens helps hair grow and fights the effects of hair loss hormones.

Valproic Acid could potentially be used to treat immune-related conditions due to its ability to modify immune cell functions.

Researchers found a genetic link for hereditary hair loss but need more analysis to identify the exact gene.

The document concludes that permanent hair loss conditions are complex, require early specific treatments, and "secondary permanent alopecias" might be a more accurate term than "secondary cicatricial alopecia."

Lymphocytes, especially CD8+ T cells, play a key role in causing alopecia areata, and targeting them may lead to new treatments.

Tofacitinib was effective in treating hair loss in two patients with alopecia universalis.

Hair usually grows back 1-3 months after treatment for anagen effluvium, and children with Loose Anagen Hair Syndrome often improve by adolescence.

Genetic discoveries are key for understanding, diagnosing, and treating inherited hair and nail disorders.

New treatments and management strategies for skin conditions like melanoma and Spitz naevi were discussed at the dermatologists' meeting.

Minoxidil boosts hair growth by triggering growth factor release from specific stem cells.

Taking 5α-reductase inhibitors with prednisolone can worsen its negative effects on metabolism.

TLR2 is important for hair growth and can be targeted to treat hair loss.

Cosmeceuticals may benefit skin health but need more research for efficacy and safety confirmation.

Ziziphus jujuba Mills may have health benefits, but more research is needed to confirm its safety and effectiveness.

PDE inhibitors, especially PDE4 inhibitors like apremilast, are effective for certain inflammatory skin conditions but have side effects and can be costly.

Janus kinase inhibitors show promise in treating alopecia areata but need more safety research.