27 citations
,
February 2006 in “International Journal of Dermatology” This study concluded that isolated trichotillomania of the eyebrows and eyelashes, identified by specific hair characteristics, may be linked to underlying obsessive-compulsive disorders in affected patients.
26 citations
,
July 2003 in “Journal of Cutaneous Medicine and Surgery” This study found that topical minoxidil solution is a safe treatment for androgenetic alopecia, with no increase in cardiovascular events or adverse pregnancy outcomes observed.
23 citations
,
February 2021 in “Journal of Endocrinological Investigation” This review discusses the impact of COVID-19 on the endocrine system and reports no clinical results; the authors emphasize the need to investigate endocrine damage during and after COVID-19 infection.
21 citations
,
January 2021 in “Therapeutic Advances in Endocrinology and Metabolism” The researchers suggest that testosterone levels might influence COVID-19 susceptibility and severity, with low levels potentially protecting against infection but possibly worsening severe disease due to cytokine storm activation.
18 citations
,
June 2021 in “Endocrinology” This review discusses the link between androgen receptor action and TMPRSS2 expression in severe COVID-19, exploring the potential of anti-androgens to mitigate disease severity in men and notes ongoing trials.
17 citations
,
May 2021 in “Journal of Assisted Reproduction and Genetics” This study reviews the mechanisms by which SARS-CoV-2 may impact male fertility, noting potential disruptions in spermatogenesis and hormone secretion, and underscores the need for follow-up in recovered men.
15 citations
,
April 2022 in “Immunology” This review discusses sex differences in immune responses to COVID-19 and highlights that males tend to experience more severe symptoms and higher mortality but reports no new clinical findings.
15 citations
,
December 2020 in “Pharmacology Research & Perspectives” This review discusses targeting host cell proteases as a novel approach to inhibit SARS-CoV-2 infection, highlighting transcriptional modulation and enzymatic inhibition as promising therapeutic strategies, but it reports no new clinical findings.
14 citations
,
July 2021 in “Reviews in endocrine and metabolic disorders” This study explores how SARS-CoV-2 interacts with endocrine organs and highlights specific endocrine molecules that help explain the progression and outcomes of COVID-19, especially in patients with certain metabolic conditions.
13 citations
,
May 2010 in “Dermatologic Clinics” Recurrent furunculosis can be managed with antibiotics, decolonization, and decontamination, with potential future use of vaccines and bacteriophage therapy.
12 citations
,
August 2020 in “Annals of Oncology” This study found that androgen deprivation therapy in prostate cancer patients was associated with fewer SARS-CoV-2 infections but did not reduce COVID-19 disease severity or hospitalizations.
12 citations
,
January 2020 in “touchREVIEWS in Endocrinology” Testosterone may both worsen and protect against COVID-19 effects in men.
10 citations
,
November 2024 in “Cureus” This systematic review identified several factors contributing to increased cardiovascular risk in women with polycystic ovary syndrome, including insulin resistance, obesity, inflammation markers, and microbiota alterations linked to elevated trimethylamine-N-oxide levels.
10 citations
,
May 2024 in “BioEssays” This review examined the role of the ion channel TRPV3 in warmth sensation and skin physiology, discussing controversies around its direct contribution to temperature perception, its involvement in skin health, and its potential as a therapeutic target for skin diseases.
10 citations
,
October 2009 in “Clinical Therapeutics” This study found that the orally disintegrating tablet and standard tablet formulations of finasteride met bioequivalence criteria in fasting healthy adult male Han Chinese volunteers, although there was a significant difference in time to maximum concentration.
8 citations
,
January 2022 in “Infectious diseases News Opinions Training” This review discusses gene polymorphisms in COVID-19 patients but reports no new clinical findings.
7 citations
,
March 2022 in “Frontiers in Genetics” This study identified genetic loci and pathways associated with long hair growth in the Tianzhu white yak, providing new insights into the genetic mechanisms of this trait.
7 citations
,
December 2020 in “Endocrine-related Cancer” This article discusses the potential role of oral DHEA, available as a 'dietary supplement' in the US, in COVID-19 morbidity and mortality, calling for clinical trials to assess its safety.
6 citations
,
February 2016 in “Journal of Microencapsulation” This study found that injectable finasteride microspheres provided a sustained drug release with a minimal initial burst in albino rabbits compared to oral suspension.
6 citations
,
September 2020 in “Journal of The American Academy of Dermatology” This letter discusses how severe baldness in men is associated with higher risk of severe COVID-19, and highlights research suggesting antiandrogen medications may improve outcomes.
6 citations
,
May 2007 in “Forensic Science Medicine and Pathology” This study found that Minoxidil can interfere with hair drug analysis for cocaine by producing peaks that obscure the detection of cocaine and its metabolites in chromatograms.
5 citations
,
December 2022 in “Viruses” This review highlights recent insights into using antiandrogens as preventive and therapeutic measures against COVID-19, emphasizing their role in blocking viral infection by modulating androgen-mediated host protease TMPRSS2 and cell entry protein ACE2, with varying success in clinical trials.
4 citations
,
March 2019 in “Journal of Pure and Applied Microbiology” This study investigated the anti-inflammatory effects of a 940nm diode laser in Wistar rats with carrageenan-induced arthritis and found that a 74J/cm² energy density significantly reduced edema and restored function, whereas 171J/cm² neared thermal exposure limits for the skin.
3 citations
,
March 2024 in “Cureus” This study found that PRP may effectively reduce TMJ pain and improve jaw function and quality of life in young adults with mild TMD.
2 citations
,
February 2023 in “International journal of molecular sciences” This study identified that copper depletion in dermal papilla cells reduced hair growth by boosting ROS levels, but ROS scavengers like NAC and ascorbic acid partially alleviated this effect.
2 citations
,
October 2020 in “Annals of Oncology” Androgen deprivation therapy might help prevent severe COVID-19, but more research is needed.
2 citations
,
October 2020 in “Annals of Oncology” This analysis discusses the role of genetic factors, particularly male hormones and specific gene variants, in influencing sex differences and potential susceptibility to severe COVID-19 outcomes, but notes that conclusive evidence is lacking, highlighting the need for larger studies.
2 citations
,
February 2019 in “bioRxiv (Cold Spring Harbor Laboratory)” This study provides the first draft of the male Asiatic lion's whole genome, revealing low genomic diversity and highlighting conservation concerns.
2 citations
,
September 2011 in “Chiang Mai Medical Journal - เชียงใหม่เวชสาร” This study demonstrated that the 5-mg generic finasteride tablet is bioequivalent to the original tablet when tested in healthy Thai male volunteers.
1 citations
,
January 2023 in “Metabolites” This review discusses the relationship between gut microbiota and polycystic ovarian syndrome (PCOS), including its potential mechanisms and the role of alterations in microbiome composition on PCOS pathophysiology.